H₂
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osteoporosis
12 papers
Delivery-method distribution
hydrogen-rich water: 5
mixed routes: 3
in vitro: 3
not specified: 1
Osteoimmunometabolic modulation via hydrogen-self-supplying magnesium-reinforced collagen membrane for enhanced guided bone regeneration.
2026 ・ Biomaterials ・ PMID 41435455
in vitro
positive
animal study
Hydrogen intervention attenuates chronic hypoxia-induced bone degeneration and multi-organ damage via modulation of the gut microbiota.
2026 ・ Bone ・ PMID 41224067
hydrogen-rich water
positive
animal study
Hydrogen activates ACOD1-itaconate pathway to ameliorate steroid-associated osteonecrosis.
2025 ・ Biomaterials ・ PMID 40411985
hydrogen-rich water
positive
animal study
Redox-Mechanisms of Molecular Hydrogen Promote Healthful Longevity.
2023 ・ Antioxidants (Basel) ・ PMID 37237854
mixed routes
not assessed
review
Molecular Hydrogen Prevents Osteoclast Activation in a Glucocorticoid-Induced Osteoporosis Zebrafish Scale Model.
2023 ・ Antioxidants (Basel) ・ PMID 36829904
hydrogen-rich water
mixed
animal study
Molecular hydrogen enhances osteogenesis in Danio rerio embryos.
2021 ・ J Fish Biol ・ PMID 33410131
hydrogen-rich water
positive
animal study
A study on the protective effect of molecular hydrogen on osteoradionecrosis of the jaw in rats.
2020 ・ Int J Oral Maxillofac Surg ・ PMID 32451233
mixed routes
positive
animal study
Preventive Effects of Drinking Hydrogen-Rich Water on Gingival Oxidative Stress and Alveolar Bone Resorption in Rats Fed a High-Fat Diet.
2017 ・ Nutrients ・ PMID 28098768
hydrogen-rich water
positive
animal study
Treatment with hydrogen molecules prevents RANKL-induced osteoclast differentiation associated with inhibition of ROS formation and inactivation of MAPK, AKT and NF-kappa B pathways in murine RAW264.7 cells.
2014 ・ J Bone Miner Metab ・ PMID 24196871
in vitro
positive
in vitro study
Treatment with hydrogen molecule alleviates TNFα-induced cell injury in osteoblast.
2013 ・ Mol Cell Biochem ・ PMID 23212446
in vitro
positive
in vitro study
Treatment of hydrogen molecule abates oxidative stress and alleviates bone loss induced by modeled microgravity in rats.
2013 ・ Osteoporos Int ・ PMID 22648000
mixed routes
positive
animal study
Methyl [hydr-oxy(phen-yl)phosphono-meth-yl]phospho-nate methanol solvate.
2008 ・ Acta Crystallogr Sect E Struct Rep Online ・ PMID 21201089
not specified
not assessed
other