# 5,6-Dihy-droxy-7,8-di-meth-oxy-flavone.
> サウスレア・インボルクラタ由来フラボン（5,6-ジヒドロキシ-7,8-ジメトキシフラボン）の結晶構造解析


## Abstract

A flavone compound with the molecular formula C17H14O6 was isolated from the petroleum ether-soluble fraction of the rare traditional Chinese medicinal herb Saussurea involucrata. X-ray crystallographic analysis revealed a nearly planar molecular geometry, with a dihedral angle of 1.89° between the benzopyranone ring system and the pendant phenyl group. The hydroxyl group at position 5 participates in a strong intramolecular hydrogen bond with the carbonyl oxygen, forming a six-membered ring motif. An additional intramolecular O–H···O contact was identified at the 6-hydroxy position. Within the crystal lattice, intermolecular O–H···O and C–H···O hydrogen bonds, together with π–π stacking interactions at distances of 3.37–3.39 Å, collectively establish a three-dimensional supramolecular network.

## Bibliographic

- **Authors**: Jing LL, Fan XF, Fan PC, He L, Jia ZP
- **Journal**: Acta Crystallogr Sect E Struct Rep Online
- **Year**: 2013
- **PMID**: [24046658](https://pubmed.ncbi.nlm.nih.gov/24046658/)
- **DOI**: [10.1107/S1600536813014451](https://doi.org/10.1107/S1600536813014451)
- **PMC**: [PMC3770373](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770373/)
- **Study type**: other
- **Delivery route**: not specified
- **Effect reported**: not assessed

## Delivery context

The delivery route is not clearly identifiable from this paper. For hydrogen intake, inhalation is the most efficient route; inhalation, however, carries explosion risk (empirical LFL of 10%; high-concentration devices are not recommended).

## Safety notes

The delivery route is not clearly identifiable from this paper. For hydrogen intake, inhalation is the most efficient route; inhalation, however, carries explosion risk (empirical LFL of 10%; high-concentration devices are not recommended).

See also:
- [Inhalation concentration and LFL / UFL](https://h2-papers.org/en/safety-notes/inhalation-concentration)
- [Consumer Affairs Agency accident cases](https://h2-papers.org/en/safety-notes/accident-cases)

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> **Cite as**: H2 Papers — PMID 24046658. https://h2-papers.org/en/papers/24046658
> **Source**: PubMed PMID [24046658](https://pubmed.ncbi.nlm.nih.gov/24046658/)