# Homogeneous isolation of nanocelluloses by controlling the shearing force and pressure in microenvironment.
> マイクロ環境におけるせん断力と圧力の制御によるナノセルロースの均一単離


## Abstract

Nanocelluloses were successfully isolated from sugarcane bagasse cellulose using dynamic high pressure microfluidization (DHPM), which achieved homogeneous dispersion by regulating shear forces and pressure within a microenvironment. Compared with conventional high pressure homogenization, DHPM required fewer processing cycles at elevated pressure. X-ray diffraction and X-ray photoelectron spectroscopy confirmed that entangled cellulose network structures were effectively dispersed, with intermolecular hydrogen bonds disrupted. Gel permeation chromatography, solid-state 13C NMR, and FT-IR analyses indicated that intramolecular hydrogen bonds remained intact. The resulting nanocelluloses exhibited reduced particle size, favorable dispersion characteristics, and lower thermal stability, suggesting potential utility in electronics, electrochemistry, biomedical applications, and the packaging and printing industries.

### Mechanism

DHPM-generated shear forces and elevated pressure within a microenvironment selectively disrupt intermolecular hydrogen bonds in cellulose networks while preserving intramolecular hydrogen bonds, enabling uniform nanocellulose dispersion.

## Bibliographic

- **Authors**: Li J, Wang Y, Wei X, Wang F, Han D, Wang Q, et al.
- **Journal**: Carbohydr Polym
- **Year**: 2014 (2014-11-26)
- **PMID**: [25256499](https://pubmed.ncbi.nlm.nih.gov/25256499/)
- **DOI**: [10.1016/j.carbpol.2014.06.085](https://doi.org/10.1016/j.carbpol.2014.06.085)
- **Study type**: other
- **Delivery route**: not specified
- **Effect reported**: not assessed

## Delivery context

The delivery route is not clearly identifiable from this paper. For hydrogen intake, inhalation is the most efficient route; inhalation, however, carries explosion risk (empirical LFL of 10%; high-concentration devices are not recommended).

## Safety notes

The delivery route is not clearly identifiable from this paper. For hydrogen intake, inhalation is the most efficient route; inhalation, however, carries explosion risk (empirical LFL of 10%; high-concentration devices are not recommended).

See also:
- [Inhalation concentration and LFL / UFL](https://h2-papers.org/en/safety-notes/inhalation-concentration)
- [Consumer Affairs Agency accident cases](https://h2-papers.org/en/safety-notes/accident-cases)

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> **Cite as**: H2 Papers — PMID 25256499. https://h2-papers.org/en/papers/25256499
> **Source**: PubMed PMID [25256499](https://pubmed.ncbi.nlm.nih.gov/25256499/)