# The Effects of Supersaturated Hydrogen-Rich Water Bathing on Biomarkers of Muscular Damage and Soreness Perception in Young Men Subjected to High-Intensity Eccentric Exercise.
> 高強度エキセントリック運動後の超飽和水素水入浴が筋損傷バイオマーカーおよび筋肉痛知覚に与える影響


## Abstract

This pilot crossover study examined whether a single 30-minute whole-body immersion in supersaturated hydrogen-rich water (HRW; 8 mg H2/L) could reduce muscle damage following high-intensity eccentric exercise in six healthy young men. Using a double-blind design, participants bathed in either HRW or control water immediately after a DOMS-inducing exercise session. At 24-hour follow-up, serum creatine kinase (CK), aldolase, and aspartate transaminase remained near baseline in the HRW group, whereas all three markers rose significantly in the control group (e.g., CK: 342 ± 309 vs. 465 ± 295 U/L). Visual Analogue Scale scores for muscle soreness were significantly lower in the HRW condition both immediately post-bath and at 24 hours. No serious adverse events were recorded, supporting the safety and potential utility of supersaturated HRW bathing for post-exercise muscle recovery.

### Mechanism

Antioxidant and anti-inflammatory properties of dissolved molecular hydrogen are proposed to limit exercise-induced oxidative stress in muscle tissue, thereby suppressing the release of damage markers such as CK, aldolase, and AST into circulation.

## Bibliographic

- **Authors**: Todorovic N, Javorac D, Stajer V, Ostojic SM
- **Journal**: J Sports Med (Hindawi Publ Corp)
- **Year**: 2020
- **PMID**: [33123594](https://pubmed.ncbi.nlm.nih.gov/33123594/)
- **DOI**: [10.1155/2020/8836070](https://doi.org/10.1155/2020/8836070)
- **PMC**: [PMC7584936](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584936/)
- **Study type**: human randomized controlled trial
- **Delivery route**: hydrogen bath
- **Effect reported**: positive

## Delivery context

Hydrogen bathing has reports of localized effects, but for systemic hydrogen intake the most efficient route is inhalation. Inhalation carries explosion risk (empirical LFL of 10%; high-concentration devices are documented in the Consumer Affairs Agency accident database and are not recommended).

## Safety notes

Hydrogen bathing has reports of localized effects, but for systemic hydrogen intake the most efficient route is inhalation. Inhalation carries explosion risk (empirical LFL of 10%; high-concentration devices are documented in the Consumer Affairs Agency accident database and are not recommended).

See also:
- [Inhalation concentration and LFL / UFL](https://h2-papers.org/en/safety-notes/inhalation-concentration)
- [Consumer Affairs Agency accident cases](https://h2-papers.org/en/safety-notes/accident-cases)

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> **Cite as**: H2 Papers — PMID 33123594. https://h2-papers.org/en/papers/33123594
> **Source**: PubMed PMID [33123594](https://pubmed.ncbi.nlm.nih.gov/33123594/)