# Hydrogen-producing Photocatalyst at Sunscreen for Athletes in Preventing and Healing Muscle-nerve-skin Injuries.
> アスリート向け光触媒含有日焼け止めによる筋肉・神経・皮膚損傷への水素の局所供給


## Abstract

A photocatalyst-doped hydrogel formulation is proposed as a sunscreen capable of continuously generating molecular hydrogen from sweat under sunlight exposure. The photocatalyst absorbs UV radiation, creating electron-hole pairs that drive water-splitting reactions within the hydrogel matrix. Sweat absorbed by the hydrogel serves as the water source, enabling sustained H2 production during outdoor activity. The generated hydrogen diffuses transdermally into underlying tissues, potentially reaching injured muscles and nerves. This delivery concept is presented as particularly suitable for athletes, since the formulation doubles as UV protection. The review further discusses potential applicability to conditions including cancer and Parkinson's disease, positioning the photocatalytic hydrogel as a versatile topical H2 delivery platform.

### Mechanism

UV-activated photocatalysts generate electron-hole pairs that split water from sweat into H2 within a hydrogel matrix. The produced hydrogen permeates the skin and diffuses to injured muscle and nerve tissues, where it is proposed to reduce oxidative stress.

## Bibliographic

- **Authors**: Sahoo P
- **Journal**: Curr Top Med Chem
- **Year**: 2023
- **PMID**: [36529921](https://pubmed.ncbi.nlm.nih.gov/36529921/)
- **DOI**: [10.2174/1568026623666221216142158](https://doi.org/10.2174/1568026623666221216142158)
- **Study type**: review
- **Delivery route**: topical application
- **Effect reported**: not assessed

## Delivery context

Topical applications have localized-effect reports, but systemic hydrogen intake is most efficient via inhalation. Inhalation carries explosion risk (empirical LFL of 10%; high-concentration devices are not recommended).

## Safety notes

Topical applications have localized-effect reports, but systemic hydrogen intake is most efficient via inhalation. Inhalation carries explosion risk (empirical LFL of 10%; high-concentration devices are not recommended).

See also:
- [Inhalation concentration and LFL / UFL](https://h2-papers.org/en/safety-notes/inhalation-concentration)
- [Consumer Affairs Agency accident cases](https://h2-papers.org/en/safety-notes/accident-cases)

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> **Cite as**: H2 Papers — PMID 36529921. https://h2-papers.org/en/papers/36529921
> **Source**: PubMed PMID [36529921](https://pubmed.ncbi.nlm.nih.gov/36529921/)