# (5-Fluoro-2,6-dioxo-1,2,3,6-tetra-hydro-pyrimidin-1-ido-κ)(1,4,8,11-tetra-aza-cyclo-tetra-decane-κ)zinc(II) perchlorate.
> 亜鉛(II)錯体における5-フルオロウラシルとシクラムの配位構造解析


## Abstract

This crystallographic study reports the coordination geometry of a zinc(II) complex in which the metal center binds to all four nitrogen atoms of the macrocyclic ligand cyclam (1,4,8,11-tetraazacyclotetradecane) and to the nitrogen atom of a deprotonated 5-fluorouracil anion. The resulting coordination polyhedron around zinc(II) is a square pyramid with a distorted basal plane defined by the four cyclam nitrogen atoms. Cyclam adopts an α-I type conformation in the solid state. Intermolecular hydrogen bonding is observed between adjacent 5-fluorouracil units and between 5-fluorouracil and the cyclam ligand, contributing to the supramolecular packing arrangement. The perchlorate anion serves as the counter-ion.

## Bibliographic

- **Authors**: Ichimaru Y, Kato K, Jin W, Kurihara M, Kurosaki H
- **Journal**: IUCrdata
- **Year**: 2024
- **PMID**: [38846558](https://pubmed.ncbi.nlm.nih.gov/38846558/)
- **DOI**: [10.1107/S2414314624004310](https://doi.org/10.1107/S2414314624004310)
- **PMC**: [PMC11151294](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11151294/)
- **Study type**: other
- **Delivery route**: not specified
- **Effect reported**: not assessed

## Delivery context

The delivery route is not clearly identifiable from this paper. For hydrogen intake, inhalation is the most efficient route; inhalation, however, carries explosion risk (empirical LFL of 10%; high-concentration devices are not recommended).

## Safety notes

The delivery route is not clearly identifiable from this paper. For hydrogen intake, inhalation is the most efficient route; inhalation, however, carries explosion risk (empirical LFL of 10%; high-concentration devices are not recommended).

See also:
- [Inhalation concentration and LFL / UFL](https://h2-papers.org/en/safety-notes/inhalation-concentration)
- [Consumer Affairs Agency accident cases](https://h2-papers.org/en/safety-notes/accident-cases)

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> **Cite as**: H2 Papers — PMID 38846558. https://h2-papers.org/en/papers/38846558
> **Source**: PubMed PMID [38846558](https://pubmed.ncbi.nlm.nih.gov/38846558/)