# Synthesis and crystal structure of ()-2-(6-chloroimidazo[1,2-]pyridin-2-yl)-3-[4-(di-methyl-amino)phen-yl]acrylo-nitrile.
> クロロイミダゾピリジン誘導体アクリロニトリル化合物の合成と結晶構造解析


## Abstract

The crystal structure of a compound incorporating a 6-chloroimidazo[1,2-a]pyridine unit linked to a dimethylaminophenyl-substituted acrylonitrile moiety was determined at 100 K. Within the crystal lattice, intermolecular C-H···N and C-H···Cl hydrogen bonds generate a network propagating along the [010] direction. C-H···π and π-π stacking interactions, together with additional intermolecular contacts, further stabilize the packing. Hirshfeld surface analysis quantified the relative contributions of key contacts: H···H at 30.2%, H···C/C···H at 28.6%, H···N/N···H at 19.9%, H···Cl/Cl···H at 12.2%, and C···C at 3.7%.

## Bibliographic

- **Authors**: Akonan L, Ziki E, N'guessan DUJ, Coulibaly S, Ouattara M, Adohi-Krou V
- **Journal**: Acta Crystallogr E Crystallogr Commun
- **Year**: 2025 (2025-09-01)
- **PMID**: [40918573](https://pubmed.ncbi.nlm.nih.gov/40918573/)
- **DOI**: [10.1107/S2056989025007248](https://doi.org/10.1107/S2056989025007248)
- **PMC**: [PMC12412701](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12412701/)
- **Study type**: other
- **Delivery route**: not specified
- **Effect reported**: not assessed

## Delivery context

The delivery route is not clearly identifiable from this paper. For hydrogen intake, inhalation is the most efficient route; inhalation, however, carries explosion risk (empirical LFL of 10%; high-concentration devices are not recommended).

## Safety notes

The delivery route is not clearly identifiable from this paper. For hydrogen intake, inhalation is the most efficient route; inhalation, however, carries explosion risk (empirical LFL of 10%; high-concentration devices are not recommended).

See also:
- [Inhalation concentration and LFL / UFL](https://h2-papers.org/en/safety-notes/inhalation-concentration)
- [Consumer Affairs Agency accident cases](https://h2-papers.org/en/safety-notes/accident-cases)

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> **Cite as**: H2 Papers — PMID 40918573. https://h2-papers.org/en/papers/40918573
> **Source**: PubMed PMID [40918573](https://pubmed.ncbi.nlm.nih.gov/40918573/)