H₂
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antioxidant enzymes
423 papers
Delivery-method distribution
hydrogen-rich water: 179
in vitro: 65
inhalation: 48
mixed routes: 47
injection / infusion: 36
not specified: 30
animal model: 8
topical application: 7
hydrogen bath: 3
Protective effects of hydrogen-rich water against acute lead-induced hepatic, renal, and testicular toxicity in rats.
2026 ・ Naunyn Schmiedebergs Arch Pharmacol ・ PMID 42115396
hydrogen-rich water
positive
animal study
Adjunctive Molecular Hydrogen Capsule Therapy in Empyema Complicated by Chronic Inflammatory Demyelinating Polyneuropathy: A Case Report.
2026 ・ In Vivo ・ PMID 42049414
hydrogen-rich water
positive
human case report
Hydrogen-Rich Water as a Performance-Enhancing Aid in National-Level Finswimmers: A Randomized, Double-Blind, Placebo-Controlled Crossover Study.
2026 ・ Int J Sports Physiol Perform ・ PMID 41991147
hydrogen-rich water
mixed
human randomized controlled trial
Green transformation of hemp seed protein: structural modification and functional enhancement with hydrogen-rich water.
2026 ・ Int J Biol Macromol ・ PMID 41932478
in vitro
positive
in vitro study
Molecular hydrogen as a treatment for ME/CFS: a mini-review of clinical evidence and mechanistic rationale.
2026 ・ Front Med (Lausanne) ・ PMID 41930109
hydrogen-rich water
positive
review
Silicon-based agent mitigates fatty liver formation in a CDAHFD60-induced MASH mouse model by enhancing hepatic function.
2026 ・ Biochem Biophys Rep ・ PMID 41890216
hydrogen-rich water
positive
animal study
Comparison of hydrogen administration methods in the treatment of radiation-induced heart disease in rats.
2026 ・ Can J Physiol Pharmacol ・ PMID 41806364
mixed routes
positive
animal study
Enhanced phytoremediation of Cd-As co-contaminated farmland using hydrogen-rich water: Mechanisms and efficiency evaluation in Solanum nigrum L․.
2026 ・ J Environ Sci (China) ・ PMID 41765536
hydrogen-rich water
positive
other
Adjunctive Molecular Hydrogen Therapy Modulates T Cell Markers and Reduces Anti-Ro Antibody in Refractory Oral Ulcers of Behçet's Disease and Sjögren's Syndrome: A Case Report.
2026 ・ In Vivo ・ PMID 41760342
hydrogen-rich water
positive
human case report
Molecular Hydrogen Improves Storage Quality of Bok Choy by Reducing Water Loss and Maintaining Cell Wall Integrity.
2026 ・ Plants (Basel) ・ PMID 41754355
in vitro
positive
other
Hydrogen-rich water improves endurance by reducing skeletal muscle oxidative stress and inflammatory responses.
2026 ・ Front Nutr ・ PMID 41641160
hydrogen-rich water
positive
animal study
Molecular hydrogen therapy in musculoskeletal conditions: An evidence-based review and critical analysis.
2026 ・ World J Orthop ・ PMID 41608485
mixed routes
positive
review
Revisiting molecular hydrogen signaling in mitochondria: Is the Rieske protein the entry point or a downstream sentinel?
2026 ・ Redox Biol ・ PMID 41496215
not specified
not assessed
review
Rhupus Syndrome With Multiple Drug Intolerances Managed by Reduced-dose Rituximab and Adjunctive Molecular Hydrogen Therapy: A Case Report.
2026 ・ In Vivo ・ PMID 41482402
hydrogen-rich water
positive
human case report
Adjuvant Molecular Hydrogen Therapy in SLE-associated Pulmonary Arterial Hypertension: A Case Report on Immunomodulatory Effects on Regulatory and Effector Lymphocytes.
2026 ・ In Vivo ・ PMID 41482388
hydrogen-rich water
positive
human case report
Emerging Clinical Applications for Molecular Hydrogen.
2026 ・ Respir Care ・ PMID 41449652
inhalation
not assessed
review
Osteoimmunometabolic modulation via hydrogen-self-supplying magnesium-reinforced collagen membrane for enhanced guided bone regeneration.
2026 ・ Biomaterials ・ PMID 41435455
in vitro
positive
animal study
Influence of hydrogen-rich water on spermatogenesis and sperm parameters in experimentally induced hypothyroidism and subclinical hypothyroidism models.
2026 ・ Reprod Toxicol ・ PMID 41421768
hydrogen-rich water
positive
animal study
Postharvest preservation of chestnuts: Combined application of hydrogen-rich water and a carboxymethyl chitosan/sodium alginate composite coating.
2026 ・ Int J Biol Macromol ・ PMID 41314584
hydrogen-rich water
positive
other
Gas Therapies for Neuro-Protection.
2026 ・ Crit Care Clin ・ PMID 41260719
inhalation
not assessed
review
Molecular hydrogen and kidney diseases: a scoping review based on scientometry and data analytics.
2026 ・ Med Gas Res ・ PMID 40826940
mixed routes
positive
review
Mechanism by which hydrogen-rich water mitigates exercise-induced fatigue: activation of the immunoresponsive gene 1-itaconate/nuclear factor erythroid 2-related factor 2/heme oxygenase-1 pathway.
2026 ・ Med Gas Res ・ PMID 40580185
hydrogen-rich water
positive
animal study
Hydrogen-rich water attenuates radiation-induced oral mucositis in mice via antioxidant and gut microbiota-stabilizing effects: a longitudinal study.
2025 ・ Gut Microbes Rep ・ PMID 41909889
hydrogen-rich water
positive
animal study
Hydrogen-Rich Water Potentiates Cannabinoid- and Gabapentinoid-Induced Analgesia in Neuropathic Pain.
2025 ・ Int J Mol Sci ・ PMID 41465581
hydrogen-rich water
positive
animal study
Exploring the Potential of Molecular Hydrogen in Different Heart Failure Models: A Review.
2025 ・ Int J Mol Sci ・ PMID 41373725
mixed routes
not assessed
review
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