H₂
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Safety Notes
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cognitive decline
111 papers
Delivery-method distribution
inhalation: 42
hydrogen-rich water: 35
mixed routes: 14
not specified: 13
injection / infusion: 2
in vitro: 2
animal model: 2
topical application: 1
Hydrogen inhalation during normoxic resuscitation improves neurological outcome in a rat model of cardiac arrest independently of targeted temperature management.
2014 ・ Circulation ・ PMID 25366995
inhalation
positive
animal study
Inhalation of hydrogen gas attenuates brain injury in mice with cecal ligation and puncture via inhibiting neuroinflammation, oxidative stress and neuronal apoptosis.
2014 ・ Brain Res ・ PMID 25251596
inhalation
positive
animal study
Molecular hydrogen in drinking water protects against neurodegenerative changes induced by traumatic brain injury.
2014 ・ PLoS One ・ PMID 25251220
hydrogen-rich water
positive
animal study
Maternal molecular hydrogen administration ameliorates rat fetal hippocampal damage caused by in utero ischemia-reperfusion.
2014 ・ Free Radic Biol Med ・ PMID 24509162
hydrogen-rich water
positive
animal study
Oral 'hydrogen water' induces neuroprotective ghrelin secretion in mice.
2013 ・ Sci Rep ・ PMID 24253616
hydrogen-rich water
positive
animal study
Molecular hydrogen: an overview of its neurobiological effects and therapeutic potential for bipolar disorder and schizophrenia.
2013 ・ Med Gas Res ・ PMID 23742229
not specified
not assessed
review
The effect of hydrogen gas on a mouse bilateral common carotid artery occlusion.
2013 ・ Acta Neurochir Suppl ・ PMID 23564105
inhalation
positive
animal study
Coadministration of hydrogen gas as part of the carrier gas mixture suppresses neuronal apoptosis and subsequent behavioral deficits caused by neonatal exposure to sevoflurane in mice.
2013 ・ Anesthesiology ・ PMID 23221861
inhalation
positive
animal study
Molecular hydrogen reduces LPS-induced neuroinflammation and promotes recovery from sickness behaviour in mice.
2012 ・ PLoS One ・ PMID 22860058
hydrogen-rich water
positive
animal study
Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.
2009 ・ PLoS One ・ PMID 19789628
hydrogen-rich water
positive
animal study
Consumption of molecular hydrogen prevents the stress-induced impairments in hippocampus-dependent learning tasks during chronic physical restraint in mice.
2009 ・ Neuropsychopharmacology ・ PMID 18563058
hydrogen-rich water
positive
animal study
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