cognitive decline

111 papers

• Hydrogen ventilation combined with mild hypothermia improves short-term neurological outcomes in a 5-day neonatal hypoxia-ischaemia piglet model.
  2019 ・ Sci Rep ・ PMID 30858437
  inhalation positive animal study
• FoxO1-mediated autophagy plays an important role in the neuroprotective effects of hydrogen in a rat model of vascular dementia.
  2019 ・ Behav Brain Res ・ PMID 29885845
  hydrogen-rich water positive animal study
• Inhalation of hydrogen gas elevates urinary 8-hydroxy-2'-deoxyguanine in Parkinson's disease.
  2018 ・ Med Gas Res ・ PMID 30713666
  inhalation null human randomized controlled trial
• Hydrogen-Rich Water Ameliorates Autistic-Like Behavioral Abnormalities in Valproic Acid-Treated Adolescent Mice Offspring.
  2018 ・ Front Behav Neurosci ・ PMID 30127728
  hydrogen-rich water positive animal study
• Molecular Hydrogen Prevents Social Deficits and Depression-Like Behaviors Induced by Low-Intensity Blast in Mice.
  2018 ・ J Neuropathol Exp Neurol ・ PMID 30053086
  inhalation positive animal study
• The Role of Gaseous Molecules in Traumatic Brain Injury: An Updated Review.
  2018 ・ Front Neurosci ・ PMID 29937711
  not specified not assessed review
• Administration of molecular hydrogen during pregnancy improves behavioral abnormalities of offspring in a maternal immune activation model.
  2018 ・ Sci Rep ・ PMID 29907804
  animal model positive animal study
• Hydrogen-rich water improves cognitive impairment gender-dependently in APP/PS1 mice without affecting Aβ clearance.
  2018 ・ Free Radic Res ・ PMID 29683360
  hydrogen-rich water mixed animal study
• Molecular hydrogen alleviates asphyxia-induced neuronal cyclooxygenase-2 expression in newborn pigs.
  2018 ・ Acta Pharmacol Sin ・ PMID 29565041
  inhalation positive animal study
• Effects of Molecular Hydrogen Assessed by an Animal Model and a Randomized Clinical Study on Mild Cognitive Impairment.
  2018 ・ Curr Alzheimer Res ・ PMID 29110615
  mixed routes mixed human randomized controlled trial
• Hydrogen-rich water for improvements of mood, anxiety, and autonomic nerve function in daily life.
  2017 ・ Med Gas Res ・ PMID 29497485
  hydrogen-rich water positive human randomized controlled trial
• Efficacy of inhaled HYdrogen on neurological outcome following BRain Ischemia During post-cardiac arrest care (HYBRID II trial): study protocol for a randomized controlled trial.
  2017 ・ Trials ・ PMID 29058596
  inhalation not assessed human randomized controlled trial
• Hydrogen gas attenuates sevoflurane neurotoxicity through inhibiting nuclear factor κ-light-chain-enhancer of activated B cells signaling and proinflammatory cytokine release in neonatal rats.
  2017 ・ Neuroreport ・ PMID 28926473
  inhalation positive animal study
• Molecular hydrogen increases resilience to stress in mice.
  2017 ・ Sci Rep ・ PMID 28852144
  inhalation positive animal study
• Molecular hydrogen in the treatment of acute and chronic neurological conditions: mechanisms of protection and routes of administration.
  2017 ・ J Clin Biochem Nutr ・ PMID 28751802
  mixed routes not assessed review
• Hydrogen Gas Inhalation Treatment in Acute Cerebral Infarction: A Randomized Controlled Clinical Study on Safety and Neuroprotection.
  2017 ・ J Stroke Cerebrovasc Dis ・ PMID 28669654
  inhalation positive human randomized controlled trial
• Molecular hydrogen inhalation attenuates postoperative cognitive impairment in rats.
  2017 ・ Neuroreport ・ PMID 28614179
  inhalation positive animal study
• Molecular Hydrogen as a Neuroprotective Agent.
  2017 ・ Curr Neuropharmacol ・ PMID 27281176
  mixed routes not assessed review
• Hydrogen-rich water improves neurological functional recovery in experimental autoimmune encephalomyelitis mice.
  2016 ・ J Neuroimmunol ・ PMID 27138092
  hydrogen-rich water positive animal study
• Suppression of ERK phosphorylation through oxidative stress is involved in the mechanism underlying sevoflurane-induced toxicity in the developing brain.
  2016 ・ Sci Rep ・ PMID 26905012
  inhalation positive animal study
• Hydrogen Inhalation is Superior to Mild Hypothermia in Improving Cardiac Function and Neurological Outcome in an Asphyxial Cardiac Arrest Model of Rats.
  2016 ・ Shock ・ PMID 26849632
  inhalation positive animal study
• Design and optimization of selective azaindole amide M1 positive allosteric modulators.
  2016 ・ Bioorg Med Chem Lett ・ PMID 26631313
  not specified not assessed other
• Potential ghrelin-mediated benefits and risks of hydrogen water.
  2015 ・ Med Hypotheses ・ PMID 25649854
  hydrogen-rich water not assessed other
• A systematic review of neuroprotective strategies after cardiac arrest: from bench to bedside (part II-comprehensive protection).
  2014 ・ Med Gas Res ・ PMID 25671079
  not specified not assessed review
• [Protective effects of inhaled hydrogen gas on cognitive function in mice with sepsis-associated encephalopathy].
  2014 ・ Zhonghua Yi Xue Za Zhi ・ PMID 25573317
  inhalation positive animal study