H₂
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Safety Notes
日本語
endothelial function
35 papers
Delivery-method distribution
inhalation: 10
hydrogen-rich water: 10
mixed routes: 4
injection / infusion: 4
in vitro: 4
not specified: 1
hydrogen bath: 1
animal model: 1
Molecular hydrogen ameliorates several characteristics of preeclampsia in the Reduced Uterine Perfusion Pressure (RUPP) rat model.
2016 ・ Free Radic Biol Med ・ PMID 27789293
mixed routes
positive
animal study
Molecular Hydrogen Alleviates Cellular Senescence in Endothelial Cells.
2016 ・ Circ J ・ PMID 27477846
in vitro
positive
in vitro study
Inhibitory Effects of Hydrogen on Proliferation and Migration of Vascular Smooth Muscle Cells via Down-Regulation of Mitogen/Activated Protein Kinase and Ezrin-Radixin-Moesin Signaling Pathways.
2016 ・ Chin J Physiol ・ PMID 26875562
mixed routes
positive
in vitro study
Molecular hydrogen protects mice against polymicrobial sepsis by ameliorating endothelial dysfunction via an Nrf2/HO-1 signaling pathway.
2015 ・ Int Immunopharmacol ・ PMID 26253656
in vitro
positive
in vitro study
Hydrogen-Rich Medium Attenuated Lipopolysaccharide-Induced Monocyte-Endothelial Cell Adhesion and Vascular Endothelial Permeability via Rho-Associated Coiled-Coil Protein Kinase.
2015 ・ Shock ・ PMID 25895142
in vitro
positive
in vitro study
Consumption of water containing over 3.5 mg of dissolved hydrogen could improve vascular endothelial function.
2014 ・ Vasc Health Risk Manag ・ PMID 25378931
hydrogen-rich water
positive
human randomized controlled trial
Protective effects of hydrogen-rich saline on ulcerative colitis rat model.
2013 ・ J Surg Res ・ PMID 23773716
injection / infusion
positive
animal study
Oral intake of hydrogen-rich water inhibits intimal hyperplasia in arterialized vein grafts in rats.
2012 ・ Cardiovasc Res ・ PMID 22287575
hydrogen-rich water
positive
animal study
[Temporary clipping and cerebral blood flow in patients with cerebral aneurysms].
2006 ・ Zh Vopr Neirokhir Im N N Burdenko ・ PMID 17125074
inhalation
not assessed
human observational study
[Application of the hydrogen washout technique to orthopedic research (author's transl)].
1981 ・ Nihon Seikeigeka Gakkai Zasshi ・ PMID 7310209
not specified
not assessed
other
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