H₂
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mitochondrial function
226 papers
Delivery-method distribution
hydrogen-rich water: 55
in vitro: 46
mixed routes: 44
not specified: 34
inhalation: 24
injection / infusion: 15
animal model: 7
hydrogen bath: 1
Mitigating environmental toxicity with hydrogen nanobubbles: A mitochondrial function-based approach to ecological restoration.
2024 ・ Environ Int ・ PMID 39515037
in vitro
positive
in vitro study
Perspective targeted diagnosis and therapy of mitochondrial bioenergetics across different diagnoses.
2024 ・ Bratisl Lek Listy ・ PMID 39487838
not specified
not assessed
review
The Protective Role of Molecular Hydrogen in Ischemia/Reperfusion Injury.
2024 ・ Int J Mol Sci ・ PMID 39063126
mixed routes
not assessed
review
Hydrogen alleviates hypoxic-ischaemic brain damage in neonatal rats by inhibiting injury of brain pericytes.
2024 ・ J Cell Mol Med ・ PMID 39001579
hydrogen-rich water
positive
animal study
Hydrogen-Rich Alkaline Water Supplementation Restores a Healthy State and Redox Balance in HO-Treated Mice.
2024 ・ Int J Mol Sci ・ PMID 38928440
hydrogen-rich water
positive
animal study
An ethically guided preclinical device for phenotyping H2 production in laboratory rodents.
2024 ・ Animal Model Exp Med ・ PMID 38925626
not specified
not assessed
animal study
Inhalation of hydrogen gas mitigates sevoflurane-induced neuronal apoptosis in the neonatal cortex and is associated with changes in protein phosphorylation.
2024 ・ J Neurochem ・ PMID 38849977
inhalation
positive
animal study
Potential role of molecular hydrogen therapy on oxidative stress and redox signaling in chronic kidney disease.
2024 ・ Biomed Pharmacother ・ PMID 38795643
mixed routes
not assessed
review
Magnesium implantation as a continuous hydrogen production generator for the treatment of myocardial infarction in rats.
2024 ・ Sci Rep ・ PMID 38745034
mixed routes
positive
animal study
Mesenchymal Stem Cell Priming: Potential Benefits of Administration of Molecular Hydrogen.
2024 ・ Pharmaceuticals (Basel) ・ PMID 38675429
mixed routes
not assessed
review
The role of hydrogen in the prevention and treatment of coronary atherosclerotic heart disease.
2024 ・ Eur J Pharmacol ・ PMID 38615891
not specified
not assessed
review
Molecular hydrogen attenuates sepsis-induced cardiomyopathy in mice by promoting autophagy.
2024 ・ BMC Anesthesiol ・ PMID 38395800
inhalation
positive
animal study
Hydrogen-rich water improves sleep consolidation and enhances forebrain neuronal activation in mice.
2024 ・ Sleep Adv ・ PMID 38264142
hydrogen-rich water
positive
animal study
Zn-Fe primary battery-enabled controlled hydrogen release in stomach for improving insulin resistance in obesity-associated type 2 diabetes.
2024 ・ Bioact Mater ・ PMID 38045569
mixed routes
positive
animal study
Clinical Use and Treatment Mechanism of Molecular Hydrogen in the Treatment of Various Kidney Diseases including Diabetic Kidney Disease.
2023 ・ Biomedicines ・ PMID 37893190
mixed routes
not assessed
review
Hydrogen-rich saline alleviates cardiomyocyte apoptosis by reducing expression of calpain1 via miR-124-3p.
2023 ・ ESC Heart Fail ・ PMID 37602925
injection / infusion
positive
animal study
The Effect of Adjuvant Therapy with Molecular Hydrogen on Endogenous Coenzyme QLevels and Platelet Mitochondrial Bioenergetics in Patients with Non-Alcoholic Fatty Liver Disease.
2023 ・ Int J Mol Sci ・ PMID 37569850
hydrogen-rich water
positive
human randomized controlled trial
Hydrogen-rich saline regulates NLRP3 inflammasome activation in sepsis-associated encephalopathy rat model.
2023 ・ Int Immunopharmacol ・ PMID 37556997
injection / infusion
positive
animal study
APOA2: New Target for Molecular Hydrogen Therapy in Sepsis-Related Lung Injury Based on Proteomic and Genomic Analysis.
2023 ・ Int J Mol Sci ・ PMID 37511084
animal model
positive
animal study
Hydrogen Therapy and Its Future Prospects for Ameliorating COVID-19: Clinical Applications, Efficacy, and Modality.
2023 ・ Biomedicines ・ PMID 37509530
mixed routes
not assessed
review
Effects of Coenzyme Q10 on the Biomarkers (Hydrogen, Methane, SCFA and TMA) and Composition of the Gut Microbiome in Rats.
2023 ・ Pharmaceuticals (Basel) ・ PMID 37242469
animal model
positive
animal study
Therapeutic Potential of Molecular Hydrogen in Metabolic Diseases from Bench to Bedside.
2023 ・ Pharmaceuticals (Basel) ・ PMID 37111299
mixed routes
not assessed
review
Fermentation of increasing ratios of grain starch and straw fiber: effects on hydrogen allocation and methanogenesis throughruminal batch culture.
2023 ・ PeerJ ・ PMID 37077306
in vitro
not assessed
in vitro study
Molecular Hydrogen: From Molecular Effects to Stem Cells Management and Tissue Regeneration.
2023 ・ Antioxidants (Basel) ・ PMID 36978884
mixed routes
not assessed
review
Molecular hydrogen promotes wound healing by inducing early epidermal stem cell proliferation and extracellular matrix deposition.
2023 ・ Inflamm Regen ・ PMID 36973725
inhalation
positive
animal study
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