-
Respiratory-physiology modeling of therapeutic hydrogen inhalation: defining the fraction of inspired hydrogen (FiH) and flow-rate requirements.
2026 ・ Respir Res ・ PMID 42050516
inhalation
not assessed
other
-
Sixty-minute inhalation of molecular hydrogen decreases blood oxygen saturation but does not alter autonomic cardiac regulation at rest in healthy females: a randomized, double-blind, placebo-controlled crossover study.
2026 ・ Can J Physiol Pharmacol ・ PMID 41401441
inhalation
mixed
human randomized controlled trial
-
Molecular Hydrogen for Outpatients with COVID-19 (Hydro-COVID): A Phase 3 Randomised, Triple-Blinded, Pragmatic, Placebo-Controlled, Multicentre Trial.
2024 ・ J Clin Med ・ PMID 39124575
hydrogen-rich water
null
human randomized controlled trial
-
Hinhalation therapy in patients with moderate COVID-19 (HCOVID): a prospective ascending-dose phase I clinical trial.
2024 ・ Antimicrob Agents Chemother ・ PMID 39016593
inhalation
positive
human case report
-
Hydrogen inhalation: in vivo rat genotoxicity tests.
2024 ・ Mutat Res Genet Toxicol Environ Mutagen ・ PMID 38432775
inhalation
null
animal study
-
Efficacy and Safety of Hydrogen Therapy in Patients with Early-Stage Interstitial Lung Disease: A Single-Center, Randomized, Parallel-Group Controlled Trial.
2023 ・ Ther Clin Risk Manag ・ PMID 38107500
hydrogen-rich water
positive
human randomized controlled trial
-
EFFECT OF ACUTE HYDROGEN-RICH WATER INTAKE ON INTRAOCULAR PRESSURE IN HEALTHY SUBJECTS.
2023 ・ Cesk Slov Oftalmol ・ PMID 37567773
hydrogen-rich water
adverse
human randomized controlled trial
-
Electrolytic hydrogen-generating bottle supplies drinking water with free/combined chlorine and ozone repressed within safety standard under hydrogen-rich conditions.
2021 ・ Med Gas Res ・ PMID 33818445
hydrogen-rich water
positive
other
-
The Effects of Supersaturated Hydrogen-Rich Water Bathing on Biomarkers of Muscular Damage and Soreness Perception in Young Men Subjected to High-Intensity Eccentric Exercise.
2020 ・ J Sports Med (Hindawi Publ Corp) ・ PMID 33123594
hydrogen bath
positive
human randomized controlled trial
-
Effects of long-term hydrogen intervention on the physiological function of rats.
2020 ・ Sci Rep ・ PMID 33116163
mixed routes
mixed
animal study
-
Low-Flow Nasal Cannula Hydrogen Therapy.
2020 ・ J Clin Med Res ・ PMID 33029275
inhalation
positive
animal study
-
Convenient methods for ingestion of molecular hydrogen: drinking, injection, and inhalation.safety lineage
2015 ・ Med Gas Res ・ PMID 26504515
mixed routes
not assessed
other
-
Hydrogen-rich water affected blood alkalinity in physically active men.
2014 ・ Res Sports Med ・ PMID 24392771
hydrogen-rich water
positive
human randomized controlled trial
-
A basic study on molecular hydrogen (H2) inhalation in acute cerebral ischemia patients for safety check with physiological parameters and measurement of blood H2 level.
2012 ・ Med Gas Res ・ PMID 22916706
inhalation
positive
human case report
-
Hydrogen(H2) treatment for acute erythymatous skin diseases. A report of 4 patients with safety data and a non-controlled feasibility study with H2 concentration measurement on two volunteers.
2012 ・ Med Gas Res ・ PMID 22607973
mixed routes
positive
human case report