H₂
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apoptosis regulation
280 papers
Delivery-method distribution
mixed routes: 61
hydrogen-rich water: 61
inhalation: 53
in vitro: 47
injection / infusion: 29
not specified: 22
topical application: 5
hydrogen bath: 1
animal model: 1
Hydrogen ventilation combined with mild hypothermia improves short-term neurological outcomes in a 5-day neonatal hypoxia-ischaemia piglet model.
2019 ・ Sci Rep ・ PMID 30858437
inhalation
positive
animal study
Morphological and molecular response of small intestine to lactulose and hydrogen-rich water in female piglets fedmycotoxins contaminated diet.
2019 ・ J Anim Sci Biotechnol ・ PMID 30805184
hydrogen-rich water
positive
animal study
The preventive and therapeutic effects of molecular hydrogen in ocular diseases and injuries where oxidative stress is involved.
2019 ・ Free Radic Res ・ PMID 30773939
mixed routes
not assessed
review
Hydrogen-rich solution attenuates cold ischemia-reperfusion injury in rat liver transplantation.
2019 ・ BMC Gastroenterol ・ PMID 30736744
injection / infusion
positive
animal study
Sustained release of bioactive hydrogen by Pd hydride nanoparticles overcomes Alzheimer's disease.
2019 ・ Biomaterials ・ PMID 30703744
injection / infusion
positive
animal study
Hydrogen gas reduces HMGB1 release in lung tissues of septic mice in an Nrf2/HO-1-dependent pathway.
2019 ・ Int Immunopharmacol ・ PMID 30660872
inhalation
positive
animal study
Molecular hydrogen: potential in mitigating oxidative-stress-induced radiation injury.
2019 ・ Can J Physiol Pharmacol ・ PMID 30543459
injection / infusion
positive
review
Brij-grafted-chitosan copolymers with function of P-glycoprotein modulation: Synthesis, characterization and in vitro investigations.
2019 ・ Carbohydr Polym ・ PMID 30366546
in vitro
positive
in vitro study
Molecular hydrogen potentiates hypothermia and prevents hypotension and fever in LPS-induced systemic inflammation.
2019 ・ Brain Behav Immun ・ PMID 30261305
inhalation
positive
animal study
FoxO1-mediated autophagy plays an important role in the neuroprotective effects of hydrogen in a rat model of vascular dementia.
2019 ・ Behav Brain Res ・ PMID 29885845
hydrogen-rich water
positive
animal study
Quantitative proteomics reveals the mechanisms of hydrogen-conferred protection against hyperoxia-induced injury in type II alveolar epithelial cells.
2018 ・ Exp Lung Res ・ PMID 30973277
in vitro
positive
in vitro study
Molecular hydrogen protects against ischemia-reperfusion injury in a mouse fatty liver model via regulating HO-1 and Sirt1 expression.
2018 ・ Sci Rep ・ PMID 30232347
injection / infusion
positive
animal study
Effects of hydrogen-occluding-silica microparticles on wound repair and cell migratory behavior of normal human esophageal epitheliocytes.
2018 ・ Med Gas Res ・ PMID 30112167
in vitro
mixed
in vitro study
Inhalation of Hydrogen Attenuates Progression of Chronic Heart Failure via Suppression of Oxidative Stress and P53 Related to Apoptosis Pathway in Rats.
2018 ・ Front Physiol ・ PMID 30108516
inhalation
positive
animal study
Translational Research of Peritoneal Dialysis Solution with Dissolved Molecular Hydrogen.
2018 ・ Contrib Nephrol ・ PMID 30041222
injection / infusion
positive
animal study
The Role of Gaseous Molecules in Traumatic Brain Injury: An Updated Review.
2018 ・ Front Neurosci ・ PMID 29937711
not specified
not assessed
review
Hydrogen gas inhalation protects against cutaneous ischaemia/reperfusion injury in a mouse model of pressure ulcer.
2018 ・ J Cell Mol Med ・ PMID 29921037
inhalation
positive
animal study
Effect of molecular hydrogen on uterine inflammation during preterm labour.
2018 ・ Biomed Rep ・ PMID 29732148
hydrogen-rich water
positive
animal study
Structural and lipid peroxidation effects of lead on rat hippocampus and its attenuation by hydrogen rich water.
2018 ・ J Chem Neuroanat ・ PMID 29694843
hydrogen-rich water
positive
animal study
[Effect of hydrogen-rich water on the chondriosome damage and cytokines in brain tissue of rats with traumatic brain injury].
2018 ・ Zhonghua Wei Zhong Bing Ji Jiu Yi Xue ・ PMID 29663991
injection / infusion
positive
animal study
A molecular dynamics approach to explore the structural characterization of cataract causing mutation R58H on human γD crystallin.
2018 ・ Mol Cell Biochem ・ PMID 29532225
in vitro
not assessed
in vitro study
Inadequate Production of Hby Gut Microbiota and Parkinson Disease.
2018 ・ Trends Endocrinol Metab ・ PMID 29478695
not specified
not assessed
review
Molecular hydrogen upregulates heat shock response and collagen biosynthesis, and downregulates cell cycles: meta-analyses of gene expression profiles.
2018 ・ Free Radic Res ・ PMID 29424253
hydrogen-rich water
positive
meta-analysis
The transfer of hydrogen from inert gas to therapeutic gas.
2017 ・ Med Gas Res ・ PMID 29497488
not specified
not assessed
review
Dissolved molecular hydrogen (H) in Peritoneal Dialysis (PD) solutions preserves mesothelial cells and peritoneal membrane integrity.
2017 ・ BMC Nephrol ・ PMID 29089029
injection / infusion
positive
animal study
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