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inhalation delivery
196 papers
Delivery-method distribution
inhalation: 150
mixed routes: 42
not specified: 2
in vitro: 2
Hydrogen gas inhalation improves delayed brain injury by alleviating early brain injury after experimental subarachnoid hemorrhage.
2020 ・ Sci Rep ・ PMID 32704088
inhalation
positive
animal study
Pharmacokinetics of a single inhalation of hydrogen gas in pigs.
2020 ・ PLoS One ・ PMID 32559239
inhalation
not assessed
animal study
Hydrogen gas alleviates blood-brain barrier impairment and cognitive dysfunction of septic mice in an Nrf2-dependent pathway.
2020 ・ Int Immunopharmacol ・ PMID 32447221
inhalation
positive
animal study
Chronic molecular hydrogen inhalation mitigates short and long-term memory loss in polymicrobial sepsis.
2020 ・ Brain Res ・ PMID 32348775
inhalation
positive
animal study
Constitutive hydrogen inhalation prevents vascular remodeling via reduction of oxidative stress.
2020 ・ PLoS One ・ PMID 32302306
inhalation
positive
animal study
A "philosophical molecule," hydrogen may overcome senescence and intractable diseases.
2020 ・ Med Gas Res ・ PMID 32189669
inhalation
not assessed
review
Inhaled molecular hydrogen attenuates intense acute exercise-induced hippocampal inflammation in sedentary rats.
2020 ・ Neurosci Lett ・ PMID 31715290
inhalation
positive
animal study
Inhalation of molecular hydrogen prevents ischemia-reperfusion liver damage during major liver resection.
2019 ・ Ann Transl Med ・ PMID 32042790
inhalation
positive
animal study
Hydrogen ameliorates lung injury in a rat model of subacute exposure to concentrated ambient PM2.5 via Aryl hydrocarbon receptor.
2019 ・ Int Immunopharmacol ・ PMID 31718930
inhalation
positive
animal study
Molecular hydrogen suppresses glioblastoma growth via inducing the glioma stem-like cell differentiation.
2019 ・ Stem Cell Res Ther ・ PMID 31113492
inhalation
positive
animal study
[Different types of molecular hydrogen donors and their pharmacokinetics in vivo].
2019 ・ Sheng Li Xue Bao ・ PMID 31008498
mixed routes
not assessed
review
Hydrogen ventilation combined with mild hypothermia improves short-term neurological outcomes in a 5-day neonatal hypoxia-ischaemia piglet model.
2019 ・ Sci Rep ・ PMID 30858437
inhalation
positive
animal study
Hydrogen gas reduces HMGB1 release in lung tissues of septic mice in an Nrf2/HO-1-dependent pathway.
2019 ・ Int Immunopharmacol ・ PMID 30660872
inhalation
positive
animal study
Molecular hydrogen potentiates hypothermia and prevents hypotension and fever in LPS-induced systemic inflammation.
2019 ・ Brain Behav Immun ・ PMID 30261305
inhalation
positive
animal study
Hydrogen gas reduces chronic intermittent hypoxia-induced hypertension by inhibiting sympathetic nerve activity and increasing vasodilator responses via the antioxidation.
2019 ・ J Cell Biochem ・ PMID 30259991
inhalation
positive
animal study
Inhalation of hydrogen gas elevates urinary 8-hydroxy-2'-deoxyguanine in Parkinson's disease.
2018 ・ Med Gas Res ・ PMID 30713666
inhalation
null
human randomized controlled trial
Beneficial effects of hydrogen gas inhalation on a murine model of allergic rhinitis.
2018 ・ Exp Ther Med ・ PMID 30542474
inhalation
positive
animal study
Protective effects of hydrogen gas against sepsis-induced acute lung injury via regulation of mitochondrial function and dynamics.
2018 ・ Int Immunopharmacol ・ PMID 30380511
inhalation
positive
animal study
Molecular hydrogen reduces acute exercise-induced inflammatory and oxidative stress status.
2018 ・ Free Radic Biol Med ・ PMID 30243702
inhalation
positive
animal study
Inhalation of Hydrogen Attenuates Progression of Chronic Heart Failure via Suppression of Oxidative Stress and P53 Related to Apoptosis Pathway in Rats.
2018 ・ Front Physiol ・ PMID 30108516
inhalation
positive
animal study
Molecular Hydrogen Prevents Social Deficits and Depression-Like Behaviors Induced by Low-Intensity Blast in Mice.
2018 ・ J Neuropathol Exp Neurol ・ PMID 30053086
inhalation
positive
animal study
Effects of Post-Treatment Hydrogen Gas Inhalation on Uveitis Induced by Endotoxin in Rats.
2018 ・ Med Sci Monit ・ PMID 29875353
inhalation
mixed
animal study
Promising novel therapy with hydrogen gas for emergency and critical care medicine.
2018 ・ Acute Med Surg ・ PMID 29657720
inhalation
not assessed
review
Molecular hydrogen alleviates asphyxia-induced neuronal cyclooxygenase-2 expression in newborn pigs.
2018 ・ Acta Pharmacol Sin ・ PMID 29565041
inhalation
positive
animal study
Efficacy of inhaled HYdrogen on neurological outcome following BRain Ischemia During post-cardiac arrest care (HYBRID II trial): study protocol for a randomized controlled trial.
2017 ・ Trials ・ PMID 29058596
inhalation
not assessed
human randomized controlled trial
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