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inhalation delivery
196 papers
Delivery-method distribution
inhalation: 150
mixed routes: 42
not specified: 2
in vitro: 2
The effect of hydrogen gas on a mouse bilateral common carotid artery occlusion.
2013 ・ Acta Neurochir Suppl ・ PMID 23564105
inhalation
positive
animal study
Coadministration of hydrogen gas as part of the carrier gas mixture suppresses neuronal apoptosis and subsequent behavioral deficits caused by neonatal exposure to sevoflurane in mice.
2013 ・ Anesthesiology ・ PMID 23221861
inhalation
positive
animal study
H(2) gas improves functional outcome after cardiac arrest to an extent comparable to therapeutic hypothermia in a rat model.
2012 ・ J Am Heart Assoc ・ PMID 23316300
inhalation
positive
animal study
Combination therapy with molecular hydrogen and hyperoxia in a murine model of polymicrobial sepsis.
2012 ・ Shock ・ PMID 23160520
inhalation
positive
animal study
A basic study on molecular hydrogen (H2) inhalation in acute cerebral ischemia patients for safety check with physiological parameters and measurement of blood H2 level.
2012 ・ Med Gas Res ・ PMID 22916706
inhalation
positive
human case report
Hydrogen(H2) treatment for acute erythymatous skin diseases. A report of 4 patients with safety data and a non-controlled feasibility study with H2 concentration measurement on two volunteers.
2012 ・ Med Gas Res ・ PMID 22607973
mixed routes
positive
human case report
Molecular hydrogen ameliorates lipopolysaccharide-induced acute lung injury in mice through reducing inflammation and apoptosis.
2012 ・ Shock ・ PMID 22508291
mixed routes
positive
animal study
Inhalation of hydrogen gas attenuates ouabain-induced auditory neuropathy in gerbils.
2012 ・ Acta Pharmacol Sin ・ PMID 22388074
inhalation
positive
animal study
Hydrogen gas ameliorates oxidative stress in early brain injury after subarachnoid hemorrhage in rats.
2012 ・ Crit Care Med ・ PMID 22336722
inhalation
positive
animal study
Molecular hydrogen is a novel antioxidant to efficiently reduce oxidative stress with potential for the improvement of mitochondrial diseases.
2012 ・ Biochim Biophys Acta ・ PMID 21621588
mixed routes
not assessed
review
Hydrogen therapy attenuates irradiation-induced lung damage by reducing oxidative stress.
2011 ・ Am J Physiol Lung Cell Mol Physiol ・ PMID 21764987
mixed routes
positive
animal study
A possible prevention strategy of radiation pneumonitis: combine radiotherapy with aerosol inhalation of hydrogen-rich solution.
2011 ・ Med Sci Monit ・ PMID 21455114
inhalation
not assessed
letter
Beneficial effects of hydrogen gas against spinal cord ischemia-reperfusion injury in rabbits.
2011 ・ Brain Res ・ PMID 21195696
inhalation
positive
animal study
Hydrogen therapy may reduce the risks related to radiation-induced oxidative stress in space flight.
2011 ・ Med Hypotheses ・ PMID 20851533
mixed routes
not assessed
other
Hydrogen gas improves survival rate and organ damage in zymosan-induced generalized inflammation model.
2010 ・ Shock ・ PMID 20351628
inhalation
positive
animal study
Protective effects of hydrogen gas on murine polymicrobial sepsis via reducing oxidative stress and HMGB1 release.
2010 ・ Shock ・ PMID 19997046
inhalation
positive
animal study
Molecular hydrogen alleviates nephrotoxicity induced by an anti-cancer drug cisplatin without compromising anti-tumor activity in mice.
2009 ・ Cancer Chemother Pharmacol ・ PMID 19148645
mixed routes
positive
animal study
Inhalation of hydrogen gas suppresses hepatic injury caused by ischemia/reperfusion through reducing oxidative stress.
2007 ・ Biochem Biophys Res Commun ・ PMID 17673169
inhalation
positive
animal study
[Temporary clipping and cerebral blood flow in patients with cerebral aneurysms].
2006 ・ Zh Vopr Neirokhir Im N N Burdenko ・ PMID 17125074
inhalation
not assessed
human observational study
Anti-inflammatory properties of molecular hydrogen: investigation on parasite-induced liver inflammation.
2001 ・ C R Acad Sci III ・ PMID 11510417
inhalation
positive
animal study
[A comparison of the measurements of local cerebral blood flow by hydrogen clearance with hydrogen inhalation and by its electrochemical generation in brain tissue].
1994 ・ Fiziol Zh Im I M Sechenova ・ PMID 7550427
mixed routes
not assessed
animal study
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