H₂
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hydroxyl radical scavenging
352 papers
Delivery-method distribution
hydrogen-rich water: 93
mixed routes: 71
inhalation: 66
in vitro: 41
injection / infusion: 34
not specified: 31
topical application: 9
animal model: 7
Inhalation of hydrogen gas reduces exacerbations of acute aortic dissection in mice.
2026 ・ Life Sci ・ PMID 42105975
inhalation
positive
animal study
Effects of Inhalation of Hydrogen Gas on Allergic Conjunctivitis Model Mice.
2026 ・ J Ocul Pharmacol Ther ・ PMID 42101321
inhalation
positive
animal study
Status quo, challenges and future directions of hydrogen medicine.
2026 ・ Fundam Res ・ PMID 41971791
mixed routes
not assessed
review
An Iron-Scavenging and Hydrogen-Releasing Microneedle Patch Suppresses Ferroptosis and Promotes Spinal Cord Repair.
2026 ・ ACS Nano ・ PMID 41960786
topical application
positive
animal study
Molecular Hydrogen Modulates the Baroreflex Activity and Reduces the Vascular Adrenoreceptor Sensitivity to Phenylephrine and Lung Inflammation in Rats with Pulmonary Hypertension.
2026 ・ Biomedicines ・ PMID 41898141
inhalation
positive
animal study
Silicon-based agent mitigates fatty liver formation in a CDAHFD60-induced MASH mouse model by enhancing hepatic function.
2026 ・ Biochem Biophys Rep ・ PMID 41890216
hydrogen-rich water
positive
animal study
The protective effects of molecular hydrogen in sepsis-associated encephalopathy: current status.
2026 ・ Eur J Pharmacol ・ PMID 41747800
mixed routes
not assessed
review
Hydrogen-rich water improves endurance by reducing skeletal muscle oxidative stress and inflammatory responses.
2026 ・ Front Nutr ・ PMID 41641160
hydrogen-rich water
positive
animal study
Molecular hydrogen therapy in musculoskeletal conditions: An evidence-based review and critical analysis.
2026 ・ World J Orthop ・ PMID 41608485
mixed routes
positive
review
Revisiting molecular hydrogen signaling in mitochondria: Is the Rieske protein the entry point or a downstream sentinel?
2026 ・ Redox Biol ・ PMID 41496215
not specified
not assessed
review
Adjuvant Molecular Hydrogen Therapy in SLE-associated Pulmonary Arterial Hypertension: A Case Report on Immunomodulatory Effects on Regulatory and Effector Lymphocytes.
2026 ・ In Vivo ・ PMID 41482388
hydrogen-rich water
positive
human case report
Emerging Clinical Applications for Molecular Hydrogen.
2026 ・ Respir Care ・ PMID 41449652
inhalation
not assessed
review
Influence of hydrogen-rich water on spermatogenesis and sperm parameters in experimentally induced hypothyroidism and subclinical hypothyroidism models.
2026 ・ Reprod Toxicol ・ PMID 41421768
hydrogen-rich water
positive
animal study
Hydrogen rescues vascular endothelial cells in obstructive sleep apnea-hypopnea syndrome by modulating nitric oxide.
2025 ・ J Thorac Dis ・ PMID 41376930
mixed routes
positive
animal study
Does Hydrogen-Rich Water Reduce Oxidative Stress in Patients with Chronic Mountain Sickness? A Randomized, Blinded, Controlled Trial.
2025 ・ High Alt Med Biol ・ PMID 41371770
hydrogen-rich water
mixed
human randomized controlled trial
The Rieske iron-sulfur protein is a primary target of molecular hydrogen.
2025 ・ Redox Biol ・ PMID 41330217
mixed routes
positive
in vitro study
Innovations in peritoneal dialysis fluid: biocompatible formulations and expanded therapeutic applications.
2025 ・ Ren Fail ・ PMID 41285129
not specified
not assessed
review
Modulating NLRP3 Inflammasome Activity and Enhancing Cortical Synaptic Plasticity: Nanoparticulate Hydrogen's Role in Relief of Post-traumatic Anxiety-like Behaviors in Rats.
2025 ・ Mol Neurobiol ・ PMID 41261203
injection / infusion
positive
animal study
Superoxide- and semiquinone-linked activation of molecular hydrogen in metal-catalyst-free solution.
2025 ・ Front Mol Biosci ・ PMID 41195421
in vitro
positive
in vitro study
Molecular mechanisms associated with effects of hydrogen molecule in liver diseases: the review of current evidence.
2025 ・ Eur J Med Res ・ PMID 41194243
mixed routes
not assessed
review
Silicon Nanostructures for Hydrogen Generation and Storage.
2025 ・ Nanomaterials (Basel) ・ PMID 41090875
not specified
not assessed
review
Transdermal hydrogen therapy for psoriasis using cavity-embedded double-conical microneedles.
2025 ・ J Control Release ・ PMID 41083007
topical application
positive
animal study
Molecular Hydrogen as an Antioxidant and Radioprotector: Mechanistic Insights from Monte Carlo Radiation-Chemical Simulations.
2025 ・ Antioxidants (Basel) ・ PMID 41008961
in vitro
positive
other
Hydrogen-rich water supplementation attenuates oxidative stress and inflammation in chronic high-altitude disease patients: A double-blind randomized placebo-controlled study.
2025 ・ Food Res Int ・ PMID 40922182
hydrogen-rich water
mixed
human randomized controlled trial
Hydrogen Gas Attenuates Toxic Metabolites and Oxidative Stress-Mediated Signaling to Inhibit Neurodegeneration and Enhance Memory in Alzheimer's Disease Models.
2025 ・ Int J Mol Sci ・ PMID 40725167
inhalation
positive
animal study
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