mitochondrial function

226 papers

• Parkinson's disease may be due to failure of melanin in the Substantia Nigra to produce molecular hydrogen from dissociation of water, to protect the brain from oxidative stress.
  2014 ・ Med Hypotheses ・ PMID 24529916
  not specified not assessed other
• Clusianone, a naturally occurring nemorosone regioisomer, uncouples rat liver mitochondria and induces HepG2 cell death.
  2014 ・ Chem Biol Interact ・ PMID 24491676
  in vitro positive in vitro study
• Treatment with hydrogen molecules prevents RANKL-induced osteoclast differentiation associated with inhibition of ROS formation and inactivation of MAPK, AKT and NF-kappa B pathways in murine RAW264.7 cells.
  2014 ・ J Bone Miner Metab ・ PMID 24196871
  in vitro positive in vitro study
• Oral 'hydrogen water' induces neuroprotective ghrelin secretion in mice.
  2013 ・ Sci Rep ・ PMID 24253616
  hydrogen-rich water positive animal study
• Multiple hits, including oxidative stress, as pathogenesis and treatment target in non-alcoholic steatohepatitis (NASH).
  2013 ・ Int J Mol Sci ・ PMID 24132155
  hydrogen-rich water not assessed review
• The evolution of molecular hydrogen: a noteworthy potential therapy with clinical significance.
  2013 ・ Med Gas Res ・ PMID 23680032
  mixed routes not assessed review
• Molecular hydrogen attenuates fatty acid uptake and lipid accumulation through downregulating CD36 expression in HepG2 cells.
  2013 ・ Med Gas Res ・ PMID 23448206
  in vitro positive in vitro study
• A novel method of preserving cardiac grafts using a hydrogen-rich water bath.
  2013 ・ J Heart Lung Transplant ・ PMID 23273745
  hydrogen bath positive animal study
• Coadministration of hydrogen gas as part of the carrier gas mixture suppresses neuronal apoptosis and subsequent behavioral deficits caused by neonatal exposure to sevoflurane in mice.
  2013 ・ Anesthesiology ・ PMID 23221861
  inhalation positive animal study
• Treatment with hydrogen molecule alleviates TNFα-induced cell injury in osteoblast.
  2013 ・ Mol Cell Biochem ・ PMID 23212446
  in vitro positive in vitro study
• Hydrogen-supplemented drinking water protects cardiac allografts from inflammation-associated deterioration.
  2012 ・ Transpl Int ・ PMID 22891787
  hydrogen-rich water positive animal study
• Molecular hydrogen as an emerging therapeutic medical gas for neurodegenerative and other diseases.
  2012 ・ Oxid Med Cell Longev ・ PMID 22720117
  mixed routes not assessed review
• The unusual cell biology of the hyperthermophilic Crenarchaeon Ignicoccus hospitalis.
  2012 ・ Antonie Van Leeuwenhoek ・ PMID 22653377
  not specified not assessed review
• Nitrogen deprivation results in photosynthetic hydrogen production in Chlamydomonas reinhardtii.
  2012 ・ Planta ・ PMID 22020754
  in vitro not assessed in vitro study
• Molecular hydrogen is a novel antioxidant to efficiently reduce oxidative stress with potential for the improvement of mitochondrial diseases.
  2012 ・ Biochim Biophys Acta ・ PMID 21621588
  mixed routes not assessed review
• Open-label trial and randomized, double-blind, placebo-controlled, crossover trial of hydrogen-enriched water for mitochondrial and inflammatory myopathies.
  2011 ・ Med Gas Res ・ PMID 22146674
  hydrogen-rich water mixed human randomized controlled trial
• The Trichomonas vaginalis hydrogenosome proteome is highly reduced relative to mitochondria, yet complex compared with mitosomes.
  2011 ・ Int J Parasitol ・ PMID 22079833
  in vitro not assessed other
• Therapeutic effects of hydrogen in animal models of Parkinson's disease.
  2011 ・ Parkinsons Dis ・ PMID 21687749
  not specified not assessed review
• Molecular hydrogen improves obesity and diabetes by inducing hepatic FGF21 and stimulating energy metabolism in db/db mice.
  2011 ・ Obesity (Silver Spring) ・ PMID 21293445
  hydrogen-rich water positive animal study
• Melatonin-mitochondria interplay in health and disease.
  2011 ・ Curr Top Med Chem ・ PMID 21244359
  not specified not assessed review
• Molecular hydrogen is protective against 6-hydroxydopamine-induced nigrostriatal degeneration in a rat model of Parkinson's disease.
  2009 ・ Neurosci Lett ・ PMID 19356598
  hydrogen-rich water positive animal study
• The hydrogenosome as a drug target.
  2008 ・ Curr Pharm Des ・ PMID 18473836
  not specified not assessed review
• The hydrogenosome peripheral vesicle: similarities with the endoplasmic reticulum.
  2008 ・ Tissue Cell ・ PMID 18031780
  in vitro not assessed in vitro study
• Melatonin, mitochondrial homeostasis and mitochondrial-related diseases.
  2002 ・ Curr Top Med Chem ・ PMID 11899097
  not specified not assessed review
• Contribution of cryofixation and freeze-substitution to analytical microscopy: a study of Tritrichomonas foetus hydrogenosomes.
  2001 ・ Microsc Res Tech ・ PMID 11279674
  in vitro not assessed in vitro study