H₂
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peroxynitrite scavenging
64 papers
Delivery-method distribution
mixed routes: 26
hydrogen-rich water: 11
not specified: 9
inhalation: 6
in vitro: 5
injection / infusion: 4
topical application: 3
Potential ghrelin-mediated benefits and risks of hydrogen water.
2015 ・ Med Hypotheses ・ PMID 25649854
hydrogen-rich water
not assessed
other
Combination therapy with nitric oxide and molecular hydrogen in a murine model of acute lung injury.
2015 ・ Shock ・ PMID 25643010
inhalation
positive
animal study
Spinal peroxynitrite contributes to remifentanil-induced postoperative hyperalgesia via enhancement of divalent metal transporter 1 without iron-responsive element-mediated iron accumulation in rats.
2015 ・ Anesthesiology ・ PMID 25501899
injection / infusion
positive
animal study
Hydrogen as a new class of radioprotective agent.
2013 ・ Int J Biol Sci ・ PMID 24155664
mixed routes
not assessed
review
Role of the Toll Like receptor (TLR) radical cycle in chronic inflammation: possible treatments targeting the TLR4 pathway.
2013 ・ Mol Neurobiol ・ PMID 23436141
not specified
not assessed
review
Treatment of hydrogen molecule abates oxidative stress and alleviates bone loss induced by modeled microgravity in rats.
2013 ・ Osteoporos Int ・ PMID 22648000
mixed routes
positive
animal study
Hydrogen-rich water prevents lipid deposition in the descending aorta in a rat periodontitis model.
2012 ・ Arch Oral Biol ・ PMID 22607937
hydrogen-rich water
positive
animal study
Molecular hydrogen and radiation protection.
2012 ・ Free Radic Res ・ PMID 22537465
mixed routes
positive
review
Open-label trial and randomized, double-blind, placebo-controlled, crossover trial of hydrogen-enriched water for mitochondrial and inflammatory myopathies.
2011 ・ Med Gas Res ・ PMID 22146674
hydrogen-rich water
mixed
human randomized controlled trial
Molecular hydrogen protects chondrocytes from oxidative stress and indirectly alters gene expressions through reducing peroxynitrite derived from nitric oxide.
2011 ・ Med Gas Res ・ PMID 22146365
in vitro
positive
in vitro study
Hydrogen therapy attenuates irradiation-induced lung damage by reducing oxidative stress.
2011 ・ Am J Physiol Lung Cell Mol Physiol ・ PMID 21764987
mixed routes
positive
animal study
A possible prevention strategy of radiation pneumonitis: combine radiotherapy with aerosol inhalation of hydrogen-rich solution.
2011 ・ Med Sci Monit ・ PMID 21455114
inhalation
not assessed
letter
Melatonin-mitochondria interplay in health and disease.
2011 ・ Curr Top Med Chem ・ PMID 21244359
not specified
not assessed
review
The hypothesis of an effective safe and novel radioprotective agent: hydrogen-rich solution.
2010 ・ West Indian Med J ・ PMID 21275114
injection / infusion
not assessed
letter
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