H₂
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Safety Notes
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reactive oxygen species
774 papers
Delivery-method distribution
hydrogen-rich water: 224
in vitro: 135
inhalation: 133
mixed routes: 118
not specified: 75
injection / infusion: 58
topical application: 14
animal model: 12
hydrogen bath: 5
Application of Molecular Hydrogen as a Novel Antioxidant in Sports Science.
2020 ・ Oxid Med Cell Longev ・ PMID 32015786
mixed routes
not assessed
review
Biological Hand CO oxidation activities are sensitive to compositional change of soil microbial communities.
2020 ・ Can J Microbiol ・ PMID 31999470
not specified
not assessed
other
Molecular Hydrogen Metabolism: a Widespread Trait of Pathogenic Bacteria and Protists.
2020 ・ Microbiol Mol Biol Rev ・ PMID 31996394
not specified
not assessed
review
Molecular hydrogen regulates PTEN-AKT-mTOR signaling via ROS to alleviate peritoneal dialysis-related peritoneal fibrosis.
2020 ・ FASEB J ・ PMID 31930571
injection / infusion
positive
animal study
Protective Effects of Hydrogen-Rich Water Against Cartilage Damage in a Rat Model of Osteoarthritis by Inhibiting Oxidative Stress, Matrix Catabolism, and Apoptosis.
2020 ・ Med Sci Monit ・ PMID 31927559
injection / infusion
positive
animal study
Hydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway.
2020 ・ BMC Cancer ・ PMID 31924176
hydrogen-rich water
positive
animal study
Combination of Korean Red Ginseng Extract and Hydrogen-Rich Water Improves Spermatogenesis and Sperm Motility in Male Mice.
2020 ・ Chin J Integr Med ・ PMID 31919748
hydrogen-rich water
positive
animal study
Molecular hydrogen suppresses superoxide generation in the mitochondrial complex I and reduced mitochondrial membrane potential.
2020 ・ Biochem Biophys Res Commun ・ PMID 31810604
in vitro
positive
in vitro study
Application of mixed metal oxide anode for the electro-oxidation/disinfection of synthetic urine: Potential of harnessing molecular hydrogen generation.
2020 ・ J Environ Manage ・ PMID 31783214
not specified
not assessed
other
Protective effects of a hydrogen-rich solution during cold ischemia in rat lung transplantation.
2020 ・ J Thorac Cardiovasc Surg ・ PMID 31780065
injection / infusion
positive
animal study
Protective effects of hydrogen‑rich saline against experimental diabetic peripheral neuropathy via activation of the mitochondrial ATP‑sensitive potassium channel channels in rats.
2020 ・ Mol Med Rep ・ PMID 31746358
injection / infusion
positive
animal study
Inhaled molecular hydrogen attenuates intense acute exercise-induced hippocampal inflammation in sedentary rats.
2020 ・ Neurosci Lett ・ PMID 31715290
inhalation
positive
animal study
Molecular hydrogen attenuates methamphetamine-induced behavioral sensitization and activation of ERK-ΔFosB signaling in the mouse nucleus accumbens.
2020 ・ Prog Neuropsychopharmacol Biol Psychiatry ・ PMID 31629777
injection / infusion
positive
animal study
A new insight into the molecular hydrogen effect on coenzyme Q and mitochondrial function of rats.
2020 ・ Can J Physiol Pharmacol ・ PMID 31536712
hydrogen-rich water
positive
animal study
Hydrogen water alleviates obliterative airway disease in mice.
2020 ・ Gen Thorac Cardiovasc Surg ・ PMID 31468277
hydrogen-rich water
positive
animal study
Case Report: Buccal administration of hydrogen-producing blend after a mild traumatic brain injury in a professional athlete.
2019 ・ F1000Res ・ PMID 32595937
topical application
positive
human case report
Inhalation of molecular hydrogen prevents ischemia-reperfusion liver damage during major liver resection.
2019 ・ Ann Transl Med ・ PMID 32042790
inhalation
positive
animal study
Effect of hydrogen-rich water on the Nrf2/ARE signaling pathway in rats with myocardial ischemia-reperfusion injury.
2019 ・ J Bioenerg Biomembr ・ PMID 31768722
hydrogen-rich water
positive
animal study
Molecular hydrogen: current knowledge on mechanism in alleviating free radical damage and diseases.
2019 ・ Acta Biochim Biophys Sin (Shanghai) ・ PMID 31738389
not specified
not assessed
review
Hydrogen ameliorates lung injury in a rat model of subacute exposure to concentrated ambient PM2.5 via Aryl hydrocarbon receptor.
2019 ・ Int Immunopharmacol ・ PMID 31718930
inhalation
positive
animal study
Organ preservation solution containing dissolved hydrogen gas from a hydrogen-absorbing alloy canister improves function of transplanted ischemic kidneys in miniature pigs.
2019 ・ PLoS One ・ PMID 31574107
injection / infusion
positive
animal study
Myalgic encephalomyelitis/chronic fatigue syndrome: From pathophysiological insights to novel therapeutic opportunities.
2019 ・ Pharmacol Res ・ PMID 31509764
not specified
not assessed
review
Lifetime of Parahydrogen in Aqueous Solutions and Human Blood.
2019 ・ Chemphyschem ・ PMID 31479580
in vitro
not assessed
in vitro study
Hydrogen on Cobalt Phosphide.
2019 ・ J Am Chem Soc ・ PMID 31479259
in vitro
not assessed
in vitro study
Effect of Htreatment in a mouse model of rheumatoid arthritis-associated interstitial lung disease.
2019 ・ J Cell Mol Med ・ PMID 31424157
hydrogen-rich water
positive
animal study
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