sepsis

48 papers

• Mitochondrial dysfunction, neuroinflammation, and associated mechanisms in sepsis-associated encephalopathy: from pathogenesis to emerging therapeutics.
  2026 ・ Front Neurosci ・ PMID 42057900
  not specified not assessed review
• The protective effects of molecular hydrogen in sepsis-associated encephalopathy: current status.
  2026 ・ Eur J Pharmacol ・ PMID 41747800
  mixed routes not assessed review
• Molecular hydrogen-mediated SIRT1 activation alleviates sepsis-associated encephalopathy by promoting mitophagy.
  2025 ・ Eur J Med Res ・ PMID 41351127
  inhalation positive animal study
• Gas as medicine: the case for hydrogen gas as a therapeutic agent for critical illness.
  2025 ・ Intensive Care Med Exp ・ PMID 40938520
  mixed routes not assessed review
• Molecular hydrogen protects against sepsis-induced cardiomyopathy through improving Golgi stress-mediated autophagy, inflammation and apoptosis.
  2025 ・ Br J Pharmacol ・ PMID 40717465
  inhalation positive animal study
• Molecular Hydrogen Therapy for SLE-PAH: Case Report on Immune Marker Modulation.
  2025 ・ In Vivo ・ PMID 40010970
  hydrogen-rich water positive human case report
• Natural hydrogen gas and engineered microalgae prevent acute lung injury in sepsis.
  2024 ・ Mater Today Bio ・ PMID 39328786
  mixed routes positive animal study
• Molecular hydrogen attenuates sepsis-induced cardiomyopathy in mice by promoting autophagy.
  2024 ・ BMC Anesthesiol ・ PMID 38395800
  inhalation positive animal study
• Attenuation of pulmonary damage in aged lipopolysaccharide-induced inflammation mice through continuous 2 % hydrogen gas inhalation: A potential therapeutic strategy for geriatric inflammation and survival.
  2023 ・ Exp Gerontol ・ PMID 37572992
  inhalation mixed animal study
• Hydrogen-rich saline regulates NLRP3 inflammasome activation in sepsis-associated encephalopathy rat model.
  2023 ・ Int Immunopharmacol ・ PMID 37556997
  injection / infusion positive animal study
• APOA2: New Target for Molecular Hydrogen Therapy in Sepsis-Related Lung Injury Based on Proteomic and Genomic Analysis.
  2023 ・ Int J Mol Sci ・ PMID 37511084
  animal model positive animal study
• Inhaled molecular hydrogen reduces hippocampal neuroinflammation, glial reactivity and ameliorates memory impairment during systemic inflammation.
  2023 ・ Brain Behav Immun Health ・ PMID 37449286
  inhalation positive animal study
• Molecular hydrogen attenuates sepsis-induced cognitive dysfunction through regulation of tau phosphorylation.
  2023 ・ Int Immunopharmacol ・ PMID 36538853
  inhalation positive animal study
• Effect of molecular hydrogen treatment on Sepsis-Associated encephalopathy in mice based on gut microbiota.
  2023 ・ CNS Neurosci Ther ・ PMID 36468415
  mixed routes positive animal study
• Effects of hydrogen-rich saline in neuroinflammation and mitochondrial dysfunction in rat model of sepsis-associated encephalopathy.
  2022 ・ J Transl Med ・ PMID 36435787
  injection / infusion positive animal study
• Emerging Trends and Hot Spots in Sepsis-Associated Encephalopathy Research From 2001 to 2021: A Bibliometric Analysis.
  2022 ・ Front Med (Lausanne) ・ PMID 35295600
  not specified not assessed other
• H2 Inhibits the Formation of Neutrophil Extracellular Traps.
  2022 ・ JACC Basic Transl Sci ・ PMID 35257042
  mixed routes positive in vitro study
• High concentration of hydrogen gas alleviates Lipopolysaccharide-induced lung injury via activating Nrf2 signaling pathway in mice.
  2021 ・ Int Immunopharmacol ・ PMID 34634688
  inhalation positive animal study
• Hydrogen gas alleviates sepsis-induced neuroinflammation and cognitive impairment through regulation of DNMT1 and DNMT3a-mediated BDNF promoter IV methylation in mice.
  2021 ・ Int Immunopharmacol ・ PMID 33773206
  inhalation positive animal study
• Hydrogen Gas Therapy Attenuates Inflammatory Pathway Signaling in Septic Mice.
  2021 ・ J Surg Res ・ PMID 33639371
  inhalation positive animal study
• Perspective of Molecular Hydrogen in the Treatment of Sepsis.
  2021 ・ Curr Pharm Des ・ PMID 32912119
  mixed routes not assessed review
• Hydrogen Gas Alleviates Sepsis-Induced Brain Injury by Improving Mitochondrial Biogenesis Through the Activation of PGC-α in Mice.
  2021 ・ Shock ・ PMID 32590694
  inhalation positive animal study
• Molecular hydrogen alleviates brain injury and cognitive impairment in a chronic sequelae model of murine polymicrobial sepsis.
  2020 ・ Exp Brain Res ・ PMID 33052428
  inhalation positive animal study
• Hydrogen Gas Inhalation Attenuates Endothelial Glycocalyx Damage and Stabilizes Hemodynamics in a Rat Hemorrhagic Shock Model.
  2020 ・ Shock ・ PMID 32804466
  inhalation positive animal study
• Hydrogen gas alleviates blood-brain barrier impairment and cognitive dysfunction of septic mice in an Nrf2-dependent pathway.
  2020 ・ Int Immunopharmacol ・ PMID 32447221
  inhalation positive animal study