sepsis

48 papers

• Chronic molecular hydrogen inhalation mitigates short and long-term memory loss in polymicrobial sepsis.
  2020 ・ Brain Res ・ PMID 32348775
  inhalation positive animal study
• Molecular hydrogen attenuates sepsis-induced neuroinflammation through regulation of microglia polarization through an mTOR-autophagy-dependent pathway.
  2020 ・ Int Immunopharmacol ・ PMID 32058932
  inhalation positive animal study
• Recent Advances in Studies of Molecular Hydrogen against Sepsis.
  2019 ・ Int J Biol Sci ・ PMID 31223285
  not specified not assessed review
• Hydrogen gas reduces HMGB1 release in lung tissues of septic mice in an Nrf2/HO-1-dependent pathway.
  2019 ・ Int Immunopharmacol ・ PMID 30660872
  inhalation positive animal study
• Molecular hydrogen potentiates hypothermia and prevents hypotension and fever in LPS-induced systemic inflammation.
  2019 ・ Brain Behav Immun ・ PMID 30261305
  inhalation positive animal study
• Protective effects of hydrogen gas against sepsis-induced acute lung injury via regulation of mitochondrial function and dynamics.
  2018 ・ Int Immunopharmacol ・ PMID 30380511
  inhalation positive animal study
• Hydrogen-Rich Saline Regulates Intestinal Barrier Dysfunction, Dysbiosis, and Bacterial Translocation in a Murine Model of Sepsis.
  2018 ・ Shock ・ PMID 29293174
  injection / infusion positive animal study
• Hydrogen Gas Protects Against Intestinal Injury in Wild Type But Not NRF2 Knockout Mice With Severe Sepsis by Regulating HO-1 and HMGB1 Release.
  2017 ・ Shock ・ PMID 28234792
  inhalation positive animal study
• Preadministration of Hydrogen-Rich Water Protects Against Lipopolysaccharide-Induced Sepsis and Attenuates Liver Injury.
  2017 ・ Shock ・ PMID 27918369
  hydrogen-rich water positive animal study
• [Role of Rho/ROCK signaling pathway in the protective effects of hydrogen against acute lung injury in septic mice].
  2016 ・ Zhonghua Wei Zhong Bing Ji Jiu Yi Xue ・ PMID 29920028
  inhalation positive animal study
• Molecular Hydrogen Therapy Ameliorates Organ Damage Induced by Sepsis.
  2016 ・ Oxid Med Cell Longev ・ PMID 27413421
  mixed routes not assessed review
• Combination therapy of molecular hydrogen and hyperoxia improves survival rate and organ damage in a zymosan-induced generalized inflammation model.
  2016 ・ Exp Ther Med ・ PMID 27284352
  inhalation positive animal study
• Molecular hydrogen inhibits lipopolysaccharide-triggered NLRP3 inflammasome activation in macrophages by targeting the mitochondrial reactive oxygen species.
  2016 ・ Biochim Biophys Acta ・ PMID 26488087
  in vitro positive in vitro study
• Molecular hydrogen protects mice against polymicrobial sepsis by ameliorating endothelial dysfunction via an Nrf2/HO-1 signaling pathway.
  2015 ・ Int Immunopharmacol ・ PMID 26253656
  in vitro positive in vitro study
• Hydrogen-Rich Medium Attenuated Lipopolysaccharide-Induced Monocyte-Endothelial Cell Adhesion and Vascular Endothelial Permeability via Rho-Associated Coiled-Coil Protein Kinase.
  2015 ・ Shock ・ PMID 25895142
  in vitro positive in vitro study
• Combination therapy with nitric oxide and molecular hydrogen in a murine model of acute lung injury.
  2015 ・ Shock ・ PMID 25643010
  inhalation positive animal study
• [Protective effects of inhaled hydrogen gas on cognitive function in mice with sepsis-associated encephalopathy].
  2014 ・ Zhonghua Yi Xue Za Zhi ・ PMID 25573317
  inhalation positive animal study
• Inhalation of hydrogen gas attenuates brain injury in mice with cecal ligation and puncture via inhibiting neuroinflammation, oxidative stress and neuronal apoptosis.
  2014 ・ Brain Res ・ PMID 25251596
  inhalation positive animal study
• Hydrogen gas presents a promising therapeutic strategy for sepsis.
  2014 ・ Biomed Res Int ・ PMID 24829918
  inhalation not assessed review
• Combination therapy with molecular hydrogen and hyperoxia in a murine model of polymicrobial sepsis.
  2012 ・ Shock ・ PMID 23160520
  inhalation positive animal study
• Molecular hydrogen ameliorates lipopolysaccharide-induced acute lung injury in mice through reducing inflammation and apoptosis.
  2012 ・ Shock ・ PMID 22508291
  mixed routes positive animal study
• Hydrogen gas improves survival rate and organ damage in zymosan-induced generalized inflammation model.
  2010 ・ Shock ・ PMID 20351628
  inhalation positive animal study
• Protective effects of hydrogen gas on murine polymicrobial sepsis via reducing oxidative stress and HMGB1 release.
  2010 ・ Shock ・ PMID 19997046
  inhalation positive animal study