N-[2-(6-メチル-4-オキソ-4H-クロメン-3-イル)-4-オキソチアゾリジン-3-イル]フラン-2-カルボキサミドのDMF溶媒和物の結晶構造
This crystallographic study reports the structure of a DMF solvate of a compound consisting of a furan-2-carboxamide moiety linked through a distorted envelope-conformation 4-oxothiazolidin-3-yl ring to a 6-methyl-4-oxo-4H-chromen-3-yl group. Intermolecular hydrogen bonding includes both strong N–H···O and weak C–H···O interactions involving the DMF solvent and the heterocyclic components. The carbonyl oxygen of DMF acts as a four-center (trifurcated) hydrogen-bond acceptor engaging the carboxamide, furan, and chromenyl groups simultaneously. Dihedral angles between the planar chromone unit and the furan and thiazolidinyl rings were determined to be 89.4° and 78.5°, respectively.
The delivery route is not clearly identifiable from this paper. For hydrogen intake, inhalation is the most efficient route; inhalation, however, carries explosion risk (empirical LFL of 10%; high-concentration devices are not recommended).
See also:
https://h2-papers.org/en/papers/21583697