PNPピンサー配位子を持つ高スピン鉄(II)ヒドリド錯体の合成・特性評価とアルケン水素化触媒への応用
A series of low-valent, high-spin iron(II) complexes incorporating a carbazole-derived PNP pincer ligand were prepared and fully characterized. Reaction of the lithiated ligand with FeCl(THF) produced the chlorido complex 1, which was subsequently converted into iron(II) alkyl derivatives (3a–3c). Exposure to KHBEt or molecular H2 generated a dimeric iron(II) hydride species, [(PNP)Fe(μ-H)]2 (4), featuring two bridging hydride ligands. Complete structural assignment was achieved through X-ray crystallography, DFT calculations, and paramagnetic NMR spectroscopy. Treatment with CO converted complexes 1 and 4 into six-coordinate diamagnetic products 2 and 5, with complex 2 existing as cis/trans isomers. Complex 4 demonstrated catalytic activity toward homogeneous alkene hydrogenation, establishing its utility as an iron-based hydrogenation catalyst.
The dinuclear iron(II) complex 4, bearing bridging hydride ligands, acts as a homogeneous catalyst by mediating H2 addition across alkene substrates via iron-hydride intermediates.
This is basic research at the cellular or molecular level. For human application, inhalation is the most promising delivery route, but inhalation carries explosion risk and concentration matters (empirical LFL of 10%; high-concentration devices are not recommended).
See also:
https://h2-papers.org/en/papers/29474088