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Crystal structure and Hirshfeld surface analysis of 4-allyl-2-meth-oxy-6-nitro-phenol.

4-アリル-2-メトキシ-6-ニトロフェノールの結晶構造およびHirshfeld表面解析

other not specified not assessed

Abstract

The title compound, synthesized by nitration of eugenol (4-allyl-2-methoxyphenol) using a nitric acid/sulfuric acid mixture, has an asymmetric unit comprising three geometrically similar independent molecules. Intramolecular hydrogen bonding between the hydroxyl and nitro groups generates an S(6) ring motif in each molecule. Crystal cohesion is maintained through intermolecular C-H···O hydrogen bonds and π-π stacking interactions between aromatic rings, with centroid-to-centroid distances ranging from 3.6583(17) to 4.0624(16) Å. Hirshfeld surface analysis combined with two-dimensional fingerprint plots identifies H···H (39.6%), O···H/H···O (37.7%), C···H/H···C (12.5%), and C···C (4.0%) contacts as the dominant contributors to crystal packing.

Bibliographic

Authors
El Ghallab Y, Derfoufi S, Ketatni EM, Saadi M, El Ammari L
Journal
Acta Crystallogr E Crystallogr Commun
Year
2020 (2020-03-01)
PMID
32148895
DOI
10.1107/S2056989020002601
PMC
PMC7057379

Delivery context

The delivery route is not clearly identifiable from this paper. For hydrogen intake, inhalation is the most efficient route; inhalation, however, carries explosion risk (empirical LFL of 10%; high-concentration devices are not recommended).

Safety notes

The delivery route is not clearly identifiable from this paper. For hydrogen intake, inhalation is the most efficient route; inhalation, however, carries explosion risk (empirical LFL of 10%; high-concentration devices are not recommended).

See also:

Cite as: H2 Papers — PMID 32148895. https://h2-papers.org/en/papers/32148895
Source: PubMed PMID 32148895