電解還元水の安全性と水素水としての有効性に関するレビュー
Multiple studies support the safety profile of alkaline electrolyzed-reduced water (ERW), yet certain animal experiments have documented tissue injury and hyperkalemia following ERW consumption. Electrode degradation at elevated pH levels may allow platinum nanoparticles and other potentially harmful metals to leach into the water, though the precise mechanism remains unclear. Clinical data indicate that ERW with pH exceeding 9.8 can induce dangerous hyperkalemia in some individuals, prompting regulatory limits at that threshold. Individuals with compromised renal function are advised to avoid ERW without medical oversight. Additional concerns encompass impaired growth, reduced absorption of minerals and vitamins, bacterial overgrowth, and mucosal lining damage. Because dissolved H2 concentrations in ERW may fall below therapeutically relevant levels, accurate measurement methods—rather than ORP-based meters—are recommended. The review concludes that further safety investigations are warranted and that pH 9.8 should not be exceeded during ERW consumption.
Electrode degradation under high-pH electrolysis conditions may cause platinum nanoparticles and other metals to leach into the water, potentially inducing tissue damage and hyperkalemia through metal toxicity mechanisms.
Hydrogen-rich water is a low-risk delivery route, but the achievable systemic hydrogen dose is bounded. For clinical applications, inhalation is the most efficient route; inhalation, however, carries explosion risk, and concentration matters (empirical LFL of 10% applies to inhalation environments; high-concentration devices are documented in the Consumer Affairs Agency accident database and are not recommended).
See also:
https://h2-papers.org/en/papers/36498838