-(4-Methoxy-2-nitrophenyl)-2-(3-methyl-2-oxo-1,2-dihydroquinoxalin-1-yl)acetamide.
キノキサリン誘導体の結晶構造解析:分子配座と分子間相互作用の検討
Abstract
This study reports the crystal structure of an acetamide compound bearing a methoxy-nitrophenyl substituent and a methyloxo-dihydroquinoxalinyl moiety. The quinoxaline bicyclic system exhibits slight puckering, with a dihedral angle of 2.07° between the two fused rings. The overall molecular geometry adopts an L-shaped arrangement, and intramolecular hydrogen bonding dictates the spatial orientation of the substituted phenyl ring. The amide nitrogen is found to be nearly planar. Crystal packing is primarily governed by C-H···O hydrogen bond networks and slipped π-stacking interactions between adjacent molecules.
Bibliographic
- Authors
- Missioui M, Mague JT, Alsubari A, Ansar M, Essassi EM, Ramli Y
- Journal
- IUCrdata
- Year
- 2023
- PMID
- 37180344
- DOI
- 10.1107/S2414314623001918
- PMC
- PMC10171322
No disease / mechanism tags on this paper. Browse evidence summaries by disease at the disease / mechanism index.
Delivery context
The delivery route is not clearly identifiable from this paper. For hydrogen intake, inhalation is the most efficient route; inhalation, however, carries explosion risk (empirical LFL of 10%; high-concentration devices are not recommended).
Safety notes
See also: