apoptosis regulation

280 papers

• Clusianone, a naturally occurring nemorosone regioisomer, uncouples rat liver mitochondria and induces HepG2 cell death.
  2014 ・ Chem Biol Interact ・ PMID 24491676
  in vitro positive in vitro study
• Treatment with hydrogen molecules prevents RANKL-induced osteoclast differentiation associated with inhibition of ROS formation and inactivation of MAPK, AKT and NF-kappa B pathways in murine RAW264.7 cells.
  2014 ・ J Bone Miner Metab ・ PMID 24196871
  in vitro positive in vitro study
• Lactulose ameliorates cerebral ischemia-reperfusion injury in rats by inducing hydrogen by activating Nrf2 expression.
  2013 ・ Free Radic Biol Med ・ PMID 23954468
  hydrogen-rich water positive animal study
• Molecular hydrogen regulates the expression of miR-9, miR-21 and miR-199 in LPS-activated retinal microglia cells.
  2013 ・ Int J Ophthalmol ・ PMID 23826519
  in vitro positive in vitro study
• Molecular hydrogen protects human lymphocyte AHH-1 cells against 12C6+ heavy ion radiation.
  2013 ・ Int J Radiat Biol ・ PMID 23786587
  in vitro positive in vitro study
• Molecular hydrogen: an overview of its neurobiological effects and therapeutic potential for bipolar disorder and schizophrenia.
  2013 ・ Med Gas Res ・ PMID 23742229
  not specified not assessed review
• The evolution of molecular hydrogen: a noteworthy potential therapy with clinical significance.
  2013 ・ Med Gas Res ・ PMID 23680032
  mixed routes not assessed review
• A novel method of preserving cardiac grafts using a hydrogen-rich water bath.
  2013 ・ J Heart Lung Transplant ・ PMID 23273745
  hydrogen bath positive animal study
• Coadministration of hydrogen gas as part of the carrier gas mixture suppresses neuronal apoptosis and subsequent behavioral deficits caused by neonatal exposure to sevoflurane in mice.
  2013 ・ Anesthesiology ・ PMID 23221861
  inhalation positive animal study
• Treatment with hydrogen molecule alleviates TNFα-induced cell injury in osteoblast.
  2013 ・ Mol Cell Biochem ・ PMID 23212446
  in vitro positive in vitro study
• Hydrogen-supplemented drinking water protects cardiac allografts from inflammation-associated deterioration.
  2012 ・ Transpl Int ・ PMID 22891787
  hydrogen-rich water positive animal study
• Molecular hydrogen and radiation protection.
  2012 ・ Free Radic Res ・ PMID 22537465
  mixed routes positive review
• Molecular hydrogen ameliorates lipopolysaccharide-induced acute lung injury in mice through reducing inflammation and apoptosis.
  2012 ・ Shock ・ PMID 22508291
  mixed routes positive animal study
• Hydrogen-rich water prevents progression of nonalcoholic steatohepatitis and accompanying hepatocarcinogenesis in mice.
  2012 ・ Hepatology ・ PMID 22505328
  hydrogen-rich water positive animal study
• Hydrogen-rich saline protects immunocytes from radiation-induced apoptosis.
  2012 ・ Med Sci Monit ・ PMID 22460088
  injection / infusion positive animal study
• Inhalation of hydrogen gas attenuates ouabain-induced auditory neuropathy in gerbils.
  2012 ・ Acta Pharmacol Sin ・ PMID 22388074
  inhalation positive animal study
• Hydrogen gas ameliorates oxidative stress in early brain injury after subarachnoid hemorrhage in rats.
  2012 ・ Crit Care Med ・ PMID 22336722
  inhalation positive animal study
• Hydrogen therapy attenuates irradiation-induced lung damage by reducing oxidative stress.
  2011 ・ Am J Physiol Lung Cell Mol Physiol ・ PMID 21764987
  mixed routes positive animal study
• Therapeutic effects of hydrogen in animal models of Parkinson's disease.
  2011 ・ Parkinsons Dis ・ PMID 21687749
  not specified not assessed review
• Melatonin-mitochondria interplay in health and disease.
  2011 ・ Curr Top Med Chem ・ PMID 21244359
  not specified not assessed review
• Beneficial effects of hydrogen gas against spinal cord ischemia-reperfusion injury in rabbits.
  2011 ・ Brain Res ・ PMID 21195696
  inhalation positive animal study
• Saturated hydrogen saline protects the lung against oxygen toxicity.
  2010 ・ Undersea Hyperb Med ・ PMID 20568549
  injection / infusion positive animal study
• Hydrogen-rich saline ameliorates the severity of l-arginine-induced acute pancreatitis in rats.
  2010 ・ Biochem Biophys Res Commun ・ PMID 20138831
  injection / infusion positive animal study
• Protection of the retina by rapid diffusion of hydrogen: administration of hydrogen-loaded eye drops in retinal ischemia-reperfusion injury.
  2010 ・ Invest Ophthalmol Vis Sci ・ PMID 19834032
  topical application positive animal study
• Hydrogen-rich saline protects myocardium against ischemia/reperfusion injury in rats.
  2009 ・ Exp Biol Med (Maywood) ・ PMID 19596825
  injection / infusion positive animal study