H₂
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Safety Notes
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anti-inflammatory
743 papers
Delivery-method distribution
hydrogen-rich water: 254
inhalation: 140
mixed routes: 129
not specified: 61
in vitro: 61
injection / infusion: 60
topical application: 17
animal model: 15
hydrogen bath: 6
Protective effect of hydrogen-rich saline on decompression sickness in rats.
2011 ・ Aviat Space Environ Med ・ PMID 21702310
injection / infusion
positive
animal study
A possible prevention strategy of radiation pneumonitis: combine radiotherapy with aerosol inhalation of hydrogen-rich solution.
2011 ・ Med Sci Monit ・ PMID 21455114
inhalation
not assessed
letter
Consumption of hydrogen water reduces paraquat-induced acute lung injury in rats.
2011 ・ J Biomed Biotechnol ・ PMID 21318114
hydrogen-rich water
positive
animal study
Molecular hydrogen improves obesity and diabetes by inducing hepatic FGF21 and stimulating energy metabolism in db/db mice.
2011 ・ Obesity (Silver Spring) ・ PMID 21293445
hydrogen-rich water
positive
animal study
Melatonin-mitochondria interplay in health and disease.
2011 ・ Curr Top Med Chem ・ PMID 21244359
not specified
not assessed
review
Beneficial effects of hydrogen gas against spinal cord ischemia-reperfusion injury in rabbits.
2011 ・ Brain Res ・ PMID 21195696
inhalation
positive
animal study
Saturated hydrogen saline protects the lung against oxygen toxicity.
2010 ・ Undersea Hyperb Med ・ PMID 20568549
injection / infusion
positive
animal study
Experimental verification of protective effect of hydrogen-rich water against cisplatin-induced nephrotoxicity in rats using dynamic contrast-enhanced CT.
2010 ・ Br J Radiol ・ PMID 20505032
hydrogen-rich water
positive
animal study
Hydrogen gas improves survival rate and organ damage in zymosan-induced generalized inflammation model.
2010 ・ Shock ・ PMID 20351628
inhalation
positive
animal study
Hydrogen-rich saline ameliorates the severity of l-arginine-induced acute pancreatitis in rats.
2010 ・ Biochem Biophys Res Commun ・ PMID 20138831
injection / infusion
positive
animal study
Hydrogen: another gas with therapeutic potential.
2010 ・ Kidney Int ・ PMID 20040921
hydrogen-rich water
positive
letter
Protective effects of hydrogen gas on murine polymicrobial sepsis via reducing oxidative stress and HMGB1 release.
2010 ・ Shock ・ PMID 19997046
inhalation
positive
animal study
Oral hydrogen water prevents chronic allograft nephropathy in rats.
2010 ・ Kidney Int ・ PMID 19907413
hydrogen-rich water
positive
animal study
Hydrogen mediates suppression of colon inflammation induced by dextran sodium sulfate.
2009 ・ Biochem Biophys Res Commun ・ PMID 19486890
hydrogen-rich water
positive
animal study
[Temporary clipping and cerebral blood flow in patients with cerebral aneurysms].
2006 ・ Zh Vopr Neirokhir Im N N Burdenko ・ PMID 17125074
inhalation
not assessed
human observational study
Melatonin, mitochondrial homeostasis and mitochondrial-related diseases.
2002 ・ Curr Top Med Chem ・ PMID 11899097
not specified
not assessed
review
Anti-inflammatory properties of molecular hydrogen: investigation on parasite-induced liver inflammation.
2001 ・ C R Acad Sci III ・ PMID 11510417
inhalation
positive
animal study
Dietary fibre and health: the role of hydrogen production.
1988 ・ Med Hypotheses ・ PMID 2849711
not specified
not assessed
other
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