H₂
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anti-inflammatory
743 papers
Delivery-method distribution
hydrogen-rich water: 254
inhalation: 140
mixed routes: 129
not specified: 61
in vitro: 61
injection / infusion: 60
topical application: 17
animal model: 15
hydrogen bath: 6
Beneficial effect of hydrogen-rich saline on cerebral vasospasm after experimental subarachnoid hemorrhage in rats.
2012 ・ J Neurosci Res ・ PMID 22589232
injection / infusion
positive
animal study
Pilot study: Effects of drinking hydrogen-rich water on muscle fatigue caused by acute exercise in elite athletes.
2012 ・ Med Gas Res ・ PMID 22520831
hydrogen-rich water
positive
human randomized controlled trial
Molecular hydrogen ameliorates lipopolysaccharide-induced acute lung injury in mice through reducing inflammation and apoptosis.
2012 ・ Shock ・ PMID 22508291
mixed routes
positive
animal study
Hydrogen-rich water prevents progression of nonalcoholic steatohepatitis and accompanying hepatocarcinogenesis in mice.
2012 ・ Hepatology ・ PMID 22505328
hydrogen-rich water
positive
animal study
Protective effects of hydrogen-rich saline in a rat model of traumatic brain injury via reducing oxidative stress.
2012 ・ J Surg Res ・ PMID 22475349
injection / infusion
positive
animal study
Hydrogen-rich saline protects immunocytes from radiation-induced apoptosis.
2012 ・ Med Sci Monit ・ PMID 22460088
injection / infusion
positive
animal study
Inhibition of hepatitis C virus NS5A by fluoro-olefin based γ-turn mimetics.
2012 ・ Bioorg Med Chem Lett ・ PMID 22425564
in vitro
positive
in vitro study
Inhalation of hydrogen gas attenuates ouabain-induced auditory neuropathy in gerbils.
2012 ・ Acta Pharmacol Sin ・ PMID 22388074
inhalation
positive
animal study
Hydrogen-rich saline protects spermatogenesis and hematopoiesis in irradiated BALB/c mice.
2012 ・ Med Sci Monit ・ PMID 22367121
injection / infusion
positive
animal study
Hydrogen gas ameliorates oxidative stress in early brain injury after subarachnoid hemorrhage in rats.
2012 ・ Crit Care Med ・ PMID 22336722
inhalation
positive
animal study
Oral intake of hydrogen-rich water inhibits intimal hyperplasia in arterialized vein grafts in rats.
2012 ・ Cardiovasc Res ・ PMID 22287575
hydrogen-rich water
positive
animal study
Hydrogen-rich saline protects retina against glutamate-induced excitotoxic injury in guinea pig.
2012 ・ Exp Eye Res ・ PMID 22154552
injection / infusion
positive
animal study
Hydrogen-rich saline prevents neointima formation after carotid balloon injury by suppressing ROS and the TNF-α/NF-κB pathway.
2012 ・ Atherosclerosis ・ PMID 22153150
injection / infusion
positive
animal study
Molecular hydrogen is a novel antioxidant to efficiently reduce oxidative stress with potential for the improvement of mitochondrial diseases.
2012 ・ Biochim Biophys Acta ・ PMID 21621588
mixed routes
not assessed
review
Open-label trial and randomized, double-blind, placebo-controlled, crossover trial of hydrogen-enriched water for mitochondrial and inflammatory myopathies.
2011 ・ Med Gas Res ・ PMID 22146674
hydrogen-rich water
mixed
human randomized controlled trial
Molecular hydrogen protects chondrocytes from oxidative stress and indirectly alters gene expressions through reducing peroxynitrite derived from nitric oxide.
2011 ・ Med Gas Res ・ PMID 22146365
in vitro
positive
in vitro study
The 2011 Medical Molecular Hydrogen Symposium: An inaugural symposium of the journal Medical Gas Research.
2011 ・ Med Gas Res ・ PMID 22146082
not specified
not assessed
letter
Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumors.
2011 ・ Med Gas Res ・ PMID 22146004
hydrogen-rich water
positive
human randomized controlled trial
Hydrogen-rich water attenuates experimental periodontitis in a rat model.
2011 ・ J Clin Periodontol ・ PMID 22092571
hydrogen-rich water
positive
animal study
Protective effect of hydrogen-rich water against gentamicin-induced nephrotoxicity in rats using blood oxygenation level-dependent MR imaging.
2011 ・ Magn Reson Med Sci ・ PMID 21959999
hydrogen-rich water
positive
animal study
Investigation of protective effect of hydrogen-rich water against cisplatin-induced nephrotoxicity in rats using blood oxygenation level-dependent magnetic resonance imaging.
2011 ・ Jpn J Radiol ・ PMID 21882093
hydrogen-rich water
positive
animal study
Hydrogen therapy attenuates irradiation-induced lung damage by reducing oxidative stress.
2011 ・ Am J Physiol Lung Cell Mol Physiol ・ PMID 21764987
mixed routes
positive
animal study
Recent progress toward hydrogen medicine: potential of molecular hydrogen for preventive and therapeutic applications.
2011 ・ Curr Pharm Des ・ PMID 21736547
mixed routes
not assessed
review
The principle and the potential approach to ROS-dependent cytotoxicity by non-pharmaceutical therapies: optimal use of medical gases with antioxidant properties.
2011 ・ Curr Pharm Des ・ PMID 21736540
not specified
not assessed
review
Molecular hydrogen inhibits lipopolysaccharide/interferon γ-induced nitric oxide production through modulation of signal transduction in macrophages.
2011 ・ Biochem Biophys Res Commun ・ PMID 21723254
mixed routes
positive
in vitro study
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