H₂
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oxidative stress
899 papers
Delivery-method distribution
hydrogen-rich water: 313
inhalation: 153
mixed routes: 150
in vitro: 103
injection / infusion: 72
not specified: 66
topical application: 19
animal model: 15
hydrogen bath: 8
Oral Administration of Si-Based Agent Attenuates Oxidative Stress and Ischemia-Reperfusion Injury in a Rat Model: A Novel Hydrogen Administration Method.
2020 ・ Front Med (Lausanne) ・ PMID 32266279
hydrogen-rich water
positive
animal study
Molecular Hydrogen Protects Human Melanocytes from Oxidative Stress by Activating Nrf2 Signaling.
2020 ・ J Invest Dermatol ・ PMID 32234461
in vitro
positive
in vitro study
A "philosophical molecule," hydrogen may overcome senescence and intractable diseases.
2020 ・ Med Gas Res ・ PMID 32189669
inhalation
not assessed
review
Hydrogen-rich water suppresses the reduction in blood total antioxidant capacity induced by 3 consecutive days of severe exercise in physically active males.
2020 ・ Med Gas Res ・ PMID 32189665
hydrogen-rich water
positive
human randomized controlled trial
Hydrogen molecules can modulate enzymatic activity and structural properties of pepsin in vitro.
2020 ・ Colloids Surf B Biointerfaces ・ PMID 32087530
in vitro
positive
in vitro study
Hydrogen-rich water alleviates cyclosporine A-induced nephrotoxicity via the Keap1/Nrf2 signaling pathway.
2020 ・ J Biochem Mol Toxicol ・ PMID 32040235
hydrogen-rich water
positive
animal study
Hydrogen Attenuates Allergic Inflammation by Reversing Energy Metabolic Pathway Switch.
2020 ・ Sci Rep ・ PMID 32029879
mixed routes
positive
human observational study
Transcriptome analysis reveals insight into molecular hydrogen-induced cadmium tolerance in alfalfa: the prominent role of sulfur and (homo)glutathione metabolism.
2020 ・ BMC Plant Biol ・ PMID 32019510
hydrogen-rich water
positive
in vitro study
Application of Molecular Hydrogen as a Novel Antioxidant in Sports Science.
2020 ・ Oxid Med Cell Longev ・ PMID 32015786
mixed routes
not assessed
review
Biological Hand CO oxidation activities are sensitive to compositional change of soil microbial communities.
2020 ・ Can J Microbiol ・ PMID 31999470
not specified
not assessed
other
Molecular hydrogen regulates PTEN-AKT-mTOR signaling via ROS to alleviate peritoneal dialysis-related peritoneal fibrosis.
2020 ・ FASEB J ・ PMID 31930571
injection / infusion
positive
animal study
Protective Effects of Hydrogen-Rich Water Against Cartilage Damage in a Rat Model of Osteoarthritis by Inhibiting Oxidative Stress, Matrix Catabolism, and Apoptosis.
2020 ・ Med Sci Monit ・ PMID 31927559
injection / infusion
positive
animal study
Hydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway.
2020 ・ BMC Cancer ・ PMID 31924176
hydrogen-rich water
positive
animal study
Combination of Korean Red Ginseng Extract and Hydrogen-Rich Water Improves Spermatogenesis and Sperm Motility in Male Mice.
2020 ・ Chin J Integr Med ・ PMID 31919748
hydrogen-rich water
positive
animal study
Molecular hydrogen suppresses superoxide generation in the mitochondrial complex I and reduced mitochondrial membrane potential.
2020 ・ Biochem Biophys Res Commun ・ PMID 31810604
in vitro
positive
in vitro study
Protective effects of a hydrogen-rich solution during cold ischemia in rat lung transplantation.
2020 ・ J Thorac Cardiovasc Surg ・ PMID 31780065
injection / infusion
positive
animal study
Protective effects of hydrogen‑rich saline against experimental diabetic peripheral neuropathy via activation of the mitochondrial ATP‑sensitive potassium channel channels in rats.
2020 ・ Mol Med Rep ・ PMID 31746358
injection / infusion
positive
animal study
Inhaled molecular hydrogen attenuates intense acute exercise-induced hippocampal inflammation in sedentary rats.
2020 ・ Neurosci Lett ・ PMID 31715290
inhalation
positive
animal study
Effects of Hydrogen-rich Water on the PI3K/AKT Signaling Pathway in Rats with Myocardial Ischemia-reperfusion Injury.
2020 ・ Curr Mol Med ・ PMID 31702499
hydrogen-rich water
positive
animal study
Acute ingestion of hydrogen-rich water does not improve incremental treadmill running performance in endurance-trained athletes.
2020 ・ Appl Physiol Nutr Metab ・ PMID 31675478
hydrogen-rich water
null
human randomized controlled trial
Effect of Hydrogen-Rich Water on Radiation-Induced Cognitive Dysfunction in Rats.
2020 ・ Radiat Res ・ PMID 31634054
hydrogen-rich water
positive
animal study
Molecular hydrogen attenuates methamphetamine-induced behavioral sensitization and activation of ERK-ΔFosB signaling in the mouse nucleus accumbens.
2020 ・ Prog Neuropsychopharmacol Biol Psychiatry ・ PMID 31629777
injection / infusion
positive
animal study
A new insight into the molecular hydrogen effect on coenzyme Q and mitochondrial function of rats.
2020 ・ Can J Physiol Pharmacol ・ PMID 31536712
hydrogen-rich water
positive
animal study
Hydrogen water alleviates obliterative airway disease in mice.
2020 ・ Gen Thorac Cardiovasc Surg ・ PMID 31468277
hydrogen-rich water
positive
animal study
Case Report: Buccal administration of hydrogen-producing blend after a mild traumatic brain injury in a professional athlete.
2019 ・ F1000Res ・ PMID 32595937
topical application
positive
human case report
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