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Acute ingestion of hydrogen-rich water does not improve incremental treadmill running performance in endurance-trained athletes.

水素水の急性摂取は持久系アスリートのトレッドミル漸増負荷走行パフォーマンスを改善しない

human randomized controlled trial hydrogen-rich water null

Abstract

This double-blind, crossover randomized controlled trial enrolled 14 endurance-trained male runners (mean age 34 years, body mass 63.1 kg) to evaluate whether acute ingestion of hydrogen-rich water (H-water) influences physiological responses and running performance. Participants consumed two 290-mL boluses of H-water or placebo: one before six submaximal 4-minute running stages and one before an incremental test to exhaustion. Cardiorespiratory variables, ratings of perceived exertion, and blood gas indices were comparable between conditions across submaximal intensities (34%–91% VO2max). Time to exhaustion (618 vs. 619 s), maximal oxygen uptake (~57 mL·kg·min), peak heart rate (184 beat·min), and perceived exertion scores were statistically indistinguishable between H-water and placebo trials. The findings indicate that this dosing regimen of H-water neither enhances endurance running capacity nor modulates buffering capacity during high-intensity exercise in trained athletes.

Mechanism

H-water was hypothesized to modulate acid-base buffering during intense exercise; however, two 290-mL doses produced no measurable changes in blood gas indices or cardiorespiratory parameters compared with placebo.

Bibliographic

Authors
Ooi CH, Ng SK, Omar EA
Journal
Appl Physiol Nutr Metab
Year
2020
PMID
31675478
DOI
10.1139/apnm-2019-0553

Tags

Delivery context

Hydrogen-rich water is a low-risk delivery route, but the achievable systemic hydrogen dose is bounded. For clinical applications, inhalation is the most efficient route; inhalation, however, carries explosion risk, and concentration matters (empirical LFL of 10% applies to inhalation environments; high-concentration devices are documented in the Consumer Affairs Agency accident database and are not recommended).

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Safety notes

Hydrogen-rich water is a low-risk delivery route, but the achievable systemic hydrogen dose is bounded. For clinical applications, inhalation is the most efficient route; inhalation, however, carries explosion risk, and concentration matters (empirical LFL of 10% applies to inhalation environments; high-concentration devices are documented in the Consumer Affairs Agency accident database and are not recommended).

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