H₂
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reactive oxygen species
774 papers
Delivery-method distribution
hydrogen-rich water: 224
in vitro: 135
inhalation: 133
mixed routes: 118
not specified: 75
injection / infusion: 58
topical application: 14
animal model: 12
hydrogen bath: 5
Mechanism by which hydrogen-rich water mitigates exercise-induced fatigue: activation of the immunoresponsive gene 1-itaconate/nuclear factor erythroid 2-related factor 2/heme oxygenase-1 pathway.
2026 ・ Med Gas Res ・ PMID 40580185
hydrogen-rich water
positive
animal study
Hydrogen-rich water attenuates radiation-induced oral mucositis in mice via antioxidant and gut microbiota-stabilizing effects: a longitudinal study.
2025 ・ Gut Microbes Rep ・ PMID 41909889
hydrogen-rich water
positive
animal study
Hydrogen-Rich Water Potentiates Cannabinoid- and Gabapentinoid-Induced Analgesia in Neuropathic Pain.
2025 ・ Int J Mol Sci ・ PMID 41465581
hydrogen-rich water
positive
animal study
Molecular Hydrogen Affords Similar Neuroprotection to Therapeutic Hypothermia in a Porcine Model of Neonatal Hypoxic-Ischemic Encephalopathy.
2025 ・ Antioxidants (Basel) ・ PMID 41462605
inhalation
positive
animal study
Hydrogen rescues vascular endothelial cells in obstructive sleep apnea-hypopnea syndrome by modulating nitric oxide.
2025 ・ J Thorac Dis ・ PMID 41376930
mixed routes
positive
animal study
Four-dimensional data independent acquisition proteomics and metabolomics reveal mechanisms of hydrogen-rich water at Zusanli (ST36) point against triple-negative breast cancer in mice.
2025 ・ J Tradit Chin Med ・ PMID 41376217
injection / infusion
positive
animal study
Does Hydrogen-Rich Water Reduce Oxidative Stress in Patients with Chronic Mountain Sickness? A Randomized, Blinded, Controlled Trial.
2025 ・ High Alt Med Biol ・ PMID 41371770
hydrogen-rich water
mixed
human randomized controlled trial
The Rieske iron-sulfur protein is a primary target of molecular hydrogen.
2025 ・ Redox Biol ・ PMID 41330217
mixed routes
positive
in vitro study
Efficacy of different nasal irrigation treatments versus placebo in allergic rhinitis: a systematic review and network meta-analysis.
2025 ・ Front Pharmacol ・ PMID 41293244
topical application
mixed
meta-analysis
Water-Promoted Molar-Level Photocatalysis and Spontaneous Product Separation with Near-Unity Quantum Efficiency.
2025 ・ J Am Chem Soc ・ PMID 41287352
in vitro
not assessed
in vitro study
Innovations in peritoneal dialysis fluid: biocompatible formulations and expanded therapeutic applications.
2025 ・ Ren Fail ・ PMID 41285129
not specified
not assessed
review
Modulating NLRP3 Inflammasome Activity and Enhancing Cortical Synaptic Plasticity: Nanoparticulate Hydrogen's Role in Relief of Post-traumatic Anxiety-like Behaviors in Rats.
2025 ・ Mol Neurobiol ・ PMID 41261203
injection / infusion
positive
animal study
Synergistic alleviation effects of salt-tolerant plant growth-promoting rhizobacteria and hydrogen-rich water on salt stress in.
2025 ・ Front Plant Sci ・ PMID 41234312
hydrogen-rich water
positive
other
Hydrogen-rich water irrigation enhances fruit quality in 'Flame Seedless' grapes by regulating chlorophyll fluorescence parameters and antioxidant activities.
2025 ・ Front Plant Sci ・ PMID 41230230
hydrogen-rich water
positive
other
Superoxide- and semiquinone-linked activation of molecular hydrogen in metal-catalyst-free solution.
2025 ・ Front Mol Biosci ・ PMID 41195421
in vitro
positive
in vitro study
Molecular mechanisms associated with effects of hydrogen molecule in liver diseases: the review of current evidence.
2025 ・ Eur J Med Res ・ PMID 41194243
mixed routes
not assessed
review
A Case Report of Adjuvant Molecular Hydrogen Therapy in Refractory Rheumatoid Arthritis With Atlantoaxial Subluxation.
2025 ・ In Vivo ・ PMID 41167690
not specified
mixed
human case report
Dynamic Immunomodulation by Hydrogen Capsule Therapy in SLE-associated Pulmonary Arterial Hypertension: A Case Report.
2025 ・ In Vivo ・ PMID 41167678
hydrogen-rich water
positive
human case report
Silicon Nanostructures for Hydrogen Generation and Storage.
2025 ・ Nanomaterials (Basel) ・ PMID 41090875
not specified
not assessed
review
Transdermal hydrogen therapy for psoriasis using cavity-embedded double-conical microneedles.
2025 ・ J Control Release ・ PMID 41083007
topical application
positive
animal study
Gut microbiota as a central mediator in hydrogen gas-induced alleviation of colitis via TLR4/NF-κB and Nrf2 pathway regulation.
2025 ・ Int Immunopharmacol ・ PMID 41076929
inhalation
positive
animal study
Hydrogen-rich gas enhances mitochondrial membrane potential and respiratory function recovery in Caco-2 cells post-ischemia-reperfusion injury.
2025 ・ Biochem Biophys Res Commun ・ PMID 41043278
in vitro
positive
in vitro study
Clinical Efficacy of Hydrogen Therapy on Acute Radiation Enteritis and Inflammatory Response in Patients with Cervical Cancer Undergoing Concurrent Chemoradiation Therapy.
2025 ・ Adv Radiat Oncol ・ PMID 41020280
inhalation
positive
human randomized controlled trial
Molecular Hydrogen as an Antioxidant and Radioprotector: Mechanistic Insights from Monte Carlo Radiation-Chemical Simulations.
2025 ・ Antioxidants (Basel) ・ PMID 41008961
in vitro
positive
other
Adjunctive molecular hydrogen therapy for refractory malar rash in systemic lupus erythematosus: A case report with immunological insights.
2025 ・ SAGE Open Med Case Rep ・ PMID 40964664
hydrogen-rich water
positive
human case report
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