H₂
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reactive oxygen species
774 papers
Delivery-method distribution
hydrogen-rich water: 224
in vitro: 135
inhalation: 133
mixed routes: 118
not specified: 75
injection / infusion: 58
topical application: 14
animal model: 12
hydrogen bath: 5
Protective effects of hydrogen gas on murine polymicrobial sepsis via reducing oxidative stress and HMGB1 release.
2010 ・ Shock ・ PMID 19997046
inhalation
positive
animal study
Oral hydrogen water prevents chronic allograft nephropathy in rats.
2010 ・ Kidney Int ・ PMID 19907413
hydrogen-rich water
positive
animal study
Protection of the retina by rapid diffusion of hydrogen: administration of hydrogen-loaded eye drops in retinal ischemia-reperfusion injury.
2010 ・ Invest Ophthalmol Vis Sci ・ PMID 19834032
topical application
positive
animal study
Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.
2009 ・ PLoS One ・ PMID 19789628
hydrogen-rich water
positive
animal study
Hydrogen-rich saline protects myocardium against ischemia/reperfusion injury in rats.
2009 ・ Exp Biol Med (Maywood) ・ PMID 19596825
injection / infusion
positive
animal study
Hydrogen mediates suppression of colon inflammation induced by dextran sodium sulfate.
2009 ・ Biochem Biophys Res Commun ・ PMID 19486890
hydrogen-rich water
positive
animal study
Molecular hydrogen is protective against 6-hydroxydopamine-induced nigrostriatal degeneration in a rat model of Parkinson's disease.
2009 ・ Neurosci Lett ・ PMID 19356598
hydrogen-rich water
positive
animal study
Engineering a synthetic dual-organism system for hydrogen production.
2009 ・ Appl Environ Microbiol ・ PMID 19201964
in vitro
not assessed
other
Molecular hydrogen alleviates nephrotoxicity induced by an anti-cancer drug cisplatin without compromising anti-tumor activity in mice.
2009 ・ Cancer Chemother Pharmacol ・ PMID 19148645
mixed routes
positive
animal study
Consumption of molecular hydrogen prevents the stress-induced impairments in hippocampus-dependent learning tasks during chronic physical restraint in mice.
2009 ・ Neuropsychopharmacology ・ PMID 18563058
hydrogen-rich water
positive
animal study
Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance.
2008 ・ Nutr Res ・ PMID 19083400
hydrogen-rich water
positive
human randomized controlled trial
The hydrogenosome as a drug target.
2008 ・ Curr Pharm Des ・ PMID 18473836
not specified
not assessed
review
Inhalation of hydrogen gas suppresses hepatic injury caused by ischemia/reperfusion through reducing oxidative stress.
2007 ・ Biochem Biophys Res Commun ・ PMID 17673169
inhalation
positive
animal study
Carbonic anhydrase inhibitors are specific openers of skeletal muscle BK channel of K+-deficient rats.
2004 ・ FASEB J ・ PMID 14766795
in vitro
not assessed
in vitro study
Targeted gene replacement of a ferredoxin gene in Trichomonas vaginalis does not lead to metronidazole resistance.
2004 ・ Mol Microbiol ・ PMID 14651615
in vitro
not assessed
in vitro study
Reactivity of partially reduced arylhydroxylamine and nitrosoarene metabolites of 2,4,6-trinitrotoluene (TNT) toward biomass and humic acids.
2002 ・ Environ Sci Technol ・ PMID 12387411
in vitro
not assessed
in vitro study
Melatonin, mitochondrial homeostasis and mitochondrial-related diseases.
2002 ・ Curr Top Med Chem ・ PMID 11899097
not specified
not assessed
review
Anti-inflammatory properties of molecular hydrogen: investigation on parasite-induced liver inflammation.
2001 ・ C R Acad Sci III ・ PMID 11510417
inhalation
positive
animal study
Characterisation and in vitro cytotoxicity of triorganophosphinegold(i) 2-mercaptobenzoate complexes.
1999 ・ Met Based Drugs ・ PMID 18475878
in vitro
positive
in vitro study
Cryo-electron energy loss spectroscopy: observations on vitrified hydrated specimens and radiation damage.
1995 ・ Ultramicroscopy ・ PMID 7571121
not specified
not assessed
other
Dependence on membrane components of methanogenesis from methyl-CoM with formaldehyde or molecular hydrogen as electron donors.
1989 ・ Eur J Biochem ・ PMID 2513188
in vitro
not assessed
in vitro study
Dietary fibre and health: the role of hydrogen production.
1988 ・ Med Hypotheses ・ PMID 2849711
not specified
not assessed
other
The radiolysis of glyceraldehyde-3-phosphate dehydrogenase.
1978 ・ Int J Radiat Biol Relat Stud Phys Chem Med ・ PMID 207651
in vitro
not assessed
in vitro study
Microbial detection method based on sensing molecular hydrogen.
1974 ・ Appl Microbiol ・ PMID 4598228
in vitro
not assessed
in vitro study
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