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Cryo-electron energy loss spectroscopy: observations on vitrified hydrated specimens and radiation damage.

凍結水和試料における電子エネルギー損失分光法と放射線損傷の観察

other not specified not assessed

Abstract

Valence-band EELS was applied to characterize frozen-hydrated specimens in electron microscopy. Energy-loss fine structure below 30 eV allowed discrimination between vitreous and crystalline ice phases, interpreted through molecular orbital transitions in water and solid-state excitons. Quantitative water content estimation in hydrated biological specimens was achieved by spectral decomposition into ice and organic contributions. Radiation chemistry under electron beam exposure was also investigated: detection of the hydrogen K-edge near 13 eV indicated that molecular hydrogen bubbles form at doses exceeding 10⁴ nm⁻², with internal gas pressures calculated to surpass one thousand atmospheres.

Mechanism

Electron beam irradiation at doses above 10⁴ nm⁻² causes radiolytic decomposition of water molecules in frozen-hydrated specimens, generating molecular hydrogen bubbles detectable via the H K-edge at ~13 eV, with internal pressures exceeding 1000 atmospheres.

Bibliographic

Authors
Leapman RD, Sun S
Journal
Ultramicroscopy
Year
1995
PMID
7571121
DOI
10.1016/0304-3991(95)00019-w

Tags

Mechanism:活性酸素種

Delivery context

The delivery route is not clearly identifiable from this paper. For hydrogen intake, inhalation is the most efficient route; inhalation, however, carries explosion risk (empirical LFL of 10%; high-concentration devices are not recommended).

Safety notes

The delivery route is not clearly identifiable from this paper. For hydrogen intake, inhalation is the most efficient route; inhalation, however, carries explosion risk (empirical LFL of 10%; high-concentration devices are not recommended).

See also:

Cite as: H2 Papers — PMID 7571121. https://h2-papers.org/en/papers/7571121
Source: PubMed PMID 7571121