Hydrogen-rich water upregulates fecal propionic acid levels in overweight adults.

Abstract

This study examined the effect of hydrogen-rich water consumption on fecal short-chain fatty acid profiles in overweight adults. Propionic acid, a gut microbiota-derived short-chain fatty acid involved in metabolic regulation and intestinal homeostasis, was measured as a primary outcome. Following the hydrogen-rich water intervention, fecal propionic acid concentrations were found to be elevated compared to baseline or control conditions. These findings suggest that hydrogen-rich water may influence gut microbial metabolite production, potentially contributing to metabolic health in individuals with excess body weight.

Mechanism

Hydrogen-rich water intake may modulate gut microbial metabolic activity, leading to increased production of propionic acid, a short-chain fatty acid with roles in metabolic and intestinal regulation.