亜鉛(II)錯体における5-フルオロウラシルとシクラムの配位構造解析
This crystallographic study reports the coordination geometry of a zinc(II) complex in which the metal center binds to all four nitrogen atoms of the macrocyclic ligand cyclam (1,4,8,11-tetraazacyclotetradecane) and to the nitrogen atom of a deprotonated 5-fluorouracil anion. The resulting coordination polyhedron around zinc(II) is a square pyramid with a distorted basal plane defined by the four cyclam nitrogen atoms. Cyclam adopts an α-I type conformation in the solid state. Intermolecular hydrogen bonding is observed between adjacent 5-fluorouracil units and between 5-fluorouracil and the cyclam ligand, contributing to the supramolecular packing arrangement. The perchlorate anion serves as the counter-ion.
The delivery route is not clearly identifiable from this paper. For hydrogen intake, inhalation is the most efficient route; inhalation, however, carries explosion risk (empirical LFL of 10%; high-concentration devices are not recommended).
See also:
https://h2-papers.org/en/papers/38846558