cognitive decline

111 papers

• Inhalation of H/O(66.7 %/33.3 %) mitigates depression-like behaviors in diabetes mellitus complicated with depression mice via suppressing inflammation and preventing hippocampal damage.
  2024 ・ Biomed Pharmacother ・ PMID 39405908
  inhalation positive animal study
• Combination of Hydrogen Inhalation and Hypothermic Temperature Control After Out-of-Hospital Cardiac Arrest: A Post hoc Analysis of the Efficacy of Inhaled Hydrogen on Neurologic Outcome Following Brain Ischemia During PostCardiac Arrest Care II Trial.
  2024 ・ Crit Care Med ・ PMID 39133068
  inhalation mixed human randomized controlled trial
• A novel intervention of molecular hydrogen on the unbalance of the gut microbiome in opioid addiction: Experimental and human studies.
  2024 ・ Biomed Pharmacother ・ PMID 39116782
  mixed routes positive other
• Realizing brain therapy with "smart medicine": mechanism and case report of molecular hydrogen inhalation for Parkinson's disease.
  2024 ・ Med Gas Res ・ PMID 39073335
  inhalation positive human case report
• The Effect of 14-Day Consumption of Hydrogen-Rich Water Alleviates Fatigue but Does Not Ameliorate Dyspnea in Long-COVID Patients: A Pilot, Single-Blind, and Randomized, Controlled Trial.
  2024 ・ Nutrients ・ PMID 38794767
  hydrogen-rich water mixed human randomized controlled trial
• Decoupling the mutual promotion of inflammation and oxidative stress mitigates cognitive decline and depression-like behavior in rmTBI mice by promoting myelin renewal and neuronal survival.
  2024 ・ Biomed Pharmacother ・ PMID 38479178
  hydrogen-rich water positive animal study
• Hydrogen-rich water improves sleep consolidation and enhances forebrain neuronal activation in mice.
  2024 ・ Sleep Adv ・ PMID 38264142
  hydrogen-rich water positive animal study
• Hyperbaric hydrogen therapy improves secondary brain injury after head trauma.
  2023 ・ Undersea Hyperb Med ・ PMID 38055881
  inhalation positive animal study
• Comprehensive brain tissue metabolomics and biological network technology to decipher the mechanism of hydrogen-rich water on Radiation-induced cognitive impairment in rats.
  2023 ・ BMC Mol Cell Biol ・ PMID 37752412
  hydrogen-rich water positive animal study
• Molecular hydrogen modulates brain glutamate/GABA-glutamine cycle in overweight humans.
  2023 ・ Arch Med Sci ・ PMID 37560746
  hydrogen-rich water positive human observational study
• Hydrogen-rich saline regulates NLRP3 inflammasome activation in sepsis-associated encephalopathy rat model.
  2023 ・ Int Immunopharmacol ・ PMID 37556997
  injection / infusion positive animal study
• Inhaled molecular hydrogen reduces hippocampal neuroinflammation, glial reactivity and ameliorates memory impairment during systemic inflammation.
  2023 ・ Brain Behav Immun Health ・ PMID 37449286
  inhalation positive animal study
• Effects of Hydrogen Gas Inhalation on Community-Dwelling Adults of Various Ages: A Single-Arm, Open-Label, Prospective Clinical Trial.
  2023 ・ Antioxidants (Basel) ・ PMID 37371971
  inhalation positive human observational study
• [Hydrogen-rich water reduces cell damage by reducing excessive autophagy in mouse neuronal cells after oxygen glucose deprivation/reoxygenation].
  2023 ・ Zhonghua Wei Zhong Bing Ji Jiu Yi Xue ・ PMID 37366131
  in vitro positive in vitro study
• Transcriptomic and metabolomic studies on the protective effect of molecular hydrogen against nuclear electromagnetic pulse-induced brain damage.
  2023 ・ Front Public Health ・ PMID 36817910
  hydrogen-rich water positive animal study
• Molecular hydrogen attenuates sepsis-induced cognitive dysfunction through regulation of tau phosphorylation.
  2023 ・ Int Immunopharmacol ・ PMID 36538853
  inhalation positive animal study
• Effects of molecular hydrogen intervention on the gut microbiome in methamphetamine abusers with mental disorder.
  2023 ・ Brain Res Bull ・ PMID 36516898
  mixed routes positive human observational study
• Effect of molecular hydrogen treatment on Sepsis-Associated encephalopathy in mice based on gut microbiota.
  2023 ・ CNS Neurosci Ther ・ PMID 36468415
  mixed routes positive animal study
• Molecular Hydrogen Mediates Neurorestorative Effects After Stroke in Diabetic Rats: the TLR4/NF-κB Inflammatory Pathway.
  2023 ・ J Neuroimmune Pharmacol ・ PMID 35895245
  inhalation positive animal study
• Pharmacokinetics of hydrogen administered intraperitoneally as hydrogen-rich saline and its effect on ischemic neuronal cell death in the brain in gerbils.
  2022 ・ PLoS One ・ PMID 36574398
  injection / infusion positive animal study
• New Treatment for the Cognitive and Emotional Deficits Linked with Paclitaxel-Induced Peripheral Neuropathy in Mice.
  2022 ・ Antioxidants (Basel) ・ PMID 36552595
  hydrogen-rich water positive animal study
• Post-COVID-19 fatigue: A systematic review.
  2022 ・ Front Psychiatry ・ PMID 36032234
  inhalation positive review
• Narrative on Hydrogen Therapy and its Clinical Applications: Safety and Efficacy.
  2022 ・ Curr Pharm Des ・ PMID 35909288
  mixed routes not assessed review
• Molecular Hydrogen Neuroprotection in Post-Ischemic Neurodegeneration in the Form of Alzheimer's Disease Proteinopathy: Underlying Mechanisms and Potential for Clinical Implementation-Fantasy or Reality?
  2022 ・ Int J Mol Sci ・ PMID 35743035
  mixed routes not assessed review
• Molecular Hydrogen as a Medical Gas for the Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Possible Efficacy Based on a Literature Review.
  2022 ・ Front Neurol ・ PMID 35493814
  mixed routes not assessed review