cognitive decline

111 papers

Research evidence summary

Q: Does molecular hydrogen help with cognitive decline?

A: Of 111 peer-reviewed papers, 73 reported a positive effect (the most common), 8 limited/mixed, 1 negative, 29 not assessed. Study mix: 20 human (9 RCT), 61 animal/basic, 26 meta-analysis or synthesis. The most studied delivery route is inhalation. The above aggregates published research and does not constitute a clinically established conclusion. See the individual paper pages for details and Safety notes for inhalation safety. (last updated 2026-05-15)

Evidence breakdown
Human20of which RCT9
Animal/basic61Synthesis/meta26
Reported effectpositive 73 ・ limited/mixed 8 ・ negative 1 ・ not assessed 29

Read the safety notes →

Delivery-method distribution

inhalation: 42 hydrogen-rich water: 35 mixed routes: 14 not specified: 13 injection / infusion: 2 in vitro: 2 animal model: 2 topical application: 1