H₂
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hydroxyl radical scavenging
352 papers
Delivery-method distribution
hydrogen-rich water: 93
mixed routes: 71
inhalation: 66
in vitro: 41
injection / infusion: 34
not specified: 31
topical application: 9
animal model: 7
Molecular hydrogen suppresses reactive astrogliosis related to oxidative injury during spinal cord injury in rats.
2014 ・ CNS Neurosci Ther ・ PMID 24685114
injection / infusion
positive
animal study
Consumption of hydrogen-rich water alleviates renal injury in spontaneous hypertensive rats.
2014 ・ Mol Cell Biochem ・ PMID 24652103
hydrogen-rich water
positive
animal study
Hydrogen-rich water delays postharvest ripening and senescence of kiwifruit.
2014 ・ Food Chem ・ PMID 24629944
hydrogen-rich water
positive
other
Production of 89Zr via the 89Y(p,n)89Zr reaction in aqueous solution: effect of solution composition on in-target chemistry.
2014 ・ Nucl Med Biol ・ PMID 24607433
not specified
not assessed
other
Dose-dependent inhibition of gastric injury by hydrogen in alkaline electrolyzed drinking water.
2014 ・ BMC Complement Altern Med ・ PMID 24589018
hydrogen-rich water
positive
animal study
Parkinson's disease may be due to failure of melanin in the Substantia Nigra to produce molecular hydrogen from dissociation of water, to protect the brain from oxidative stress.
2014 ・ Med Hypotheses ・ PMID 24529916
not specified
not assessed
other
Maternal molecular hydrogen administration ameliorates rat fetal hippocampal damage caused by in utero ischemia-reperfusion.
2014 ・ Free Radic Biol Med ・ PMID 24509162
hydrogen-rich water
positive
animal study
Effect of a hydrogen (H2)-enriched solution on the albumin redox of hemodialysis patients.
2014 ・ Hemodial Int ・ PMID 24274030
injection / infusion
positive
human randomized controlled trial
Effect of Treadmill Exercise and Hydrogen-rich Water Intake on Serum Oxidative and Anti-oxidative Metabolites in Serum of Thoroughbred Horses.
2013 ・ J Equine Sci ・ PMID 24833996
hydrogen-rich water
positive
animal study
Hydrogen as a new class of radioprotective agent.
2013 ・ Int J Biol Sci ・ PMID 24155664
mixed routes
not assessed
review
Multiple hits, including oxidative stress, as pathogenesis and treatment target in non-alcoholic steatohepatitis (NASH).
2013 ・ Int J Mol Sci ・ PMID 24132155
hydrogen-rich water
not assessed
review
Effect of hydrogen-rich water on oxidative stress, liver function, and viral load in patients with chronic hepatitis B.
2013 ・ Clin Transl Sci ・ PMID 24127924
hydrogen-rich water
mixed
human randomized controlled trial
Lactulose ameliorates cerebral ischemia-reperfusion injury in rats by inducing hydrogen by activating Nrf2 expression.
2013 ・ Free Radic Biol Med ・ PMID 23954468
hydrogen-rich water
positive
animal study
Molecular hydrogen: new antioxidant and anti-inflammatory therapy for rheumatoid arthritis and related diseases.
2013 ・ Curr Pharm Des ・ PMID 23859555
mixed routes
not assessed
review
Molecular hydrogen consumption in the human body during the inhalation of hydrogen gas.
2013 ・ Adv Exp Med Biol ・ PMID 23852510
inhalation
not assessed
human observational study
Transperitoneal administration of dissolved hydrogen for peritoneal dialysis patients: a novel approach to suppress oxidative stress in the peritoneal cavity.
2013 ・ Med Gas Res ・ PMID 23816239
injection / infusion
positive
human case report
Molecular hydrogen protects human lymphocyte AHH-1 cells against 12C6+ heavy ion radiation.
2013 ・ Int J Radiat Biol ・ PMID 23786587
in vitro
positive
in vitro study
Molecular hydrogen: an overview of its neurobiological effects and therapeutic potential for bipolar disorder and schizophrenia.
2013 ・ Med Gas Res ・ PMID 23742229
not specified
not assessed
review
The evolution of molecular hydrogen: a noteworthy potential therapy with clinical significance.
2013 ・ Med Gas Res ・ PMID 23680032
mixed routes
not assessed
review
The effect of hydrogen gas on a mouse bilateral common carotid artery occlusion.
2013 ・ Acta Neurochir Suppl ・ PMID 23564105
inhalation
positive
animal study
Pilot study of H₂ therapy in Parkinson's disease: a randomized double-blind placebo-controlled trial.
2013 ・ Mov Disord ・ PMID 23400965
hydrogen-rich water
positive
human randomized controlled trial
Lactulose mediates suppression of dextran sodium sulfate-induced colon inflammation by increasing hydrogen production.
2013 ・ Dig Dis Sci ・ PMID 23371012
mixed routes
positive
animal study
Coadministration of hydrogen gas as part of the carrier gas mixture suppresses neuronal apoptosis and subsequent behavioral deficits caused by neonatal exposure to sevoflurane in mice.
2013 ・ Anesthesiology ・ PMID 23221861
inhalation
positive
animal study
H(2) gas improves functional outcome after cardiac arrest to an extent comparable to therapeutic hypothermia in a rat model.
2012 ・ J Am Heart Assoc ・ PMID 23316300
inhalation
positive
animal study
Combination therapy with molecular hydrogen and hyperoxia in a murine model of polymicrobial sepsis.
2012 ・ Shock ・ PMID 23160520
inhalation
positive
animal study
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