H₂
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hydroxyl radical scavenging
352 papers
Delivery-method distribution
hydrogen-rich water: 93
mixed routes: 71
inhalation: 66
in vitro: 41
injection / infusion: 34
not specified: 31
topical application: 9
animal model: 7
Hydrogen-rich water-alleviated ultraviolet-B-triggered oxidative damage is partially associated with the manipulation of the metabolism of (iso)flavonoids and antioxidant defence in Medicago sativa.
2015 ・ Funct Plant Biol ・ PMID 32480752
hydrogen-rich water
positive
other
[Initiation, development and potential of hydrogen medicine: Toward therapeutic and preventive applications of molecular hydrogen against a variety of diseases].
2015 ・ Seikagaku ・ PMID 26571560
mixed routes
not assessed
review
Maternal molecular hydrogen administration on lipopolysaccharide-induced mouse fetal brain injury.
2015 ・ J Clin Biochem Nutr ・ PMID 26566302
hydrogen-rich water
positive
animal study
Hydrogen-rich saline may be an effective and specific novel treatment for osteoradionecrosis of the jaw.
2015 ・ Ther Clin Risk Manag ・ PMID 26508867
injection / infusion
not assessed
letter
Intravenous infusion of H2-saline suppresses oxidative stress and elevates antioxidant potential in Thoroughbred horses after racing exercise.
2015 ・ Sci Rep ・ PMID 26493164
injection / infusion
positive
animal study
Beneficial biological effects and the underlying mechanisms of molecular hydrogen - comprehensive review of 321 original articles.
2015 ・ Med Gas Res ・ PMID 26483953
mixed routes
not assessed
review
The Evaluation and Quantitation of Dihydrogen Metabolism Using Deuterium Isotope in Rats.
2015 ・ PLoS One ・ PMID 26103048
mixed routes
positive
animal study
Hydrogen ameliorates pulmonary hypertension in rats by anti-inflammatory and antioxidant effects.
2015 ・ J Thorac Cardiovasc Surg ・ PMID 26095621
hydrogen-rich water
positive
animal study
Improvement of psoriasis-associated arthritis and skin lesions by treatment with molecular hydrogen: A report of three cases.
2015 ・ Mol Med Rep ・ PMID 25936373
mixed routes
positive
human case report
Hydrogen improves neurological function through attenuation of blood-brain barrier disruption in spontaneously hypertensive stroke-prone rats.
2015 ・ BMC Neurosci ・ PMID 25925889
hydrogen-rich water
positive
animal study
Eumelanin-driven production of molecular hydrogen: A novel element of skin defense?
2015 ・ Med Hypotheses ・ PMID 25920542
not specified
not assessed
other
Hydrogen-Rich Medium Attenuated Lipopolysaccharide-Induced Monocyte-Endothelial Cell Adhesion and Vascular Endothelial Permeability via Rho-Associated Coiled-Coil Protein Kinase.
2015 ・ Shock ・ PMID 25895142
in vitro
positive
in vitro study
Molecular hydrogen as a novel antioxidant: overview of the advantages of hydrogen for medical applications.
2015 ・ Methods Enzymol ・ PMID 25747486
mixed routes
not assessed
review
Potential ghrelin-mediated benefits and risks of hydrogen water.
2015 ・ Med Hypotheses ・ PMID 25649854
hydrogen-rich water
not assessed
other
Stimulation of human damaged sperm motility with hydrogen molecule.
2015 ・ Med Gas Res ・ PMID 25649433
in vitro
positive
in vitro study
Molecular hydrogen in sports medicine: new therapeutic perspectives.
2015 ・ Int J Sports Med ・ PMID 25525953
mixed routes
not assessed
review
[Protective effects of inhaled hydrogen gas on cognitive function in mice with sepsis-associated encephalopathy].
2014 ・ Zhonghua Yi Xue Za Zhi ・ PMID 25573317
inhalation
positive
animal study
Consumption of water containing over 3.5 mg of dissolved hydrogen could improve vascular endothelial function.
2014 ・ Vasc Health Risk Manag ・ PMID 25378931
hydrogen-rich water
positive
human randomized controlled trial
Inhaled hydrogen gas therapy for prevention of noise-induced hearing loss through reducing reactive oxygen species.
2014 ・ Neurosci Res ・ PMID 25196919
inhalation
positive
animal study
Hydrogen protects auditory hair cells from cisplatin-induced free radicals.
2014 ・ Neurosci Lett ・ PMID 25064701
in vitro
positive
in vitro study
Effects of hydrogen-rich water on aging periodontal tissues in rats.
2014 ・ Sci Rep ・ PMID 24985521
hydrogen-rich water
mixed
animal study
Oral intake of hydrogen-rich water ameliorated chlorpyrifos-induced neurotoxicity in rats.
2014 ・ Toxicol Appl Pharmacol ・ PMID 24967689
hydrogen-rich water
positive
animal study
Molecular hydrogen attenuates neuropathic pain in mice.
2014 ・ PLoS One ・ PMID 24941001
hydrogen-rich water
positive
animal study
Therapeutic efficacy of infused molecular hydrogen in saline on rheumatoid arthritis: a randomized, double-blind, placebo-controlled pilot study.
2014 ・ Int Immunopharmacol ・ PMID 24929023
injection / infusion
positive
human randomized controlled trial
Molecular hydrogen as a preventive and therapeutic medical gas: initiation, development and potential of hydrogen medicine.
2014 ・ Pharmacol Ther ・ PMID 24769081
mixed routes
not assessed
review
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