H₂
Papers
Search
Topics
Safety Notes
日本語
intestinal injury
54 papers
Delivery-method distribution
hydrogen-rich water: 22
not specified: 9
inhalation: 8
mixed routes: 5
injection / infusion: 4
in vitro: 3
animal model: 3
Molecular hydrogen suppresses gut inflammation and pyroptosis in ulcerative colitis through promoting PKM2 lactylation to block NLRP3 inflammasome activation.
2026 ・ Int Immunopharmacol ・ PMID 42035551
mixed routes
positive
animal study
Hydrogen Molecule Delivery System to Ischemic Intestine Using Resuscitative Endovascular Balloon Occlusion of Aorta in Hemorrhagic Shock-A Proof-of-Concept Study.
2026 ・ Biomedicines ・ PMID 41751354
injection / infusion
positive
animal study
Hydrogen intervention attenuates chronic hypoxia-induced bone degeneration and multi-organ damage via modulation of the gut microbiota.
2026 ・ Bone ・ PMID 41224067
hydrogen-rich water
positive
animal study
Hydrogen-rich water alleviates neuropathic pain through the modulation of bile acid/Takeda G-protein-coupled receptor 5-mediated autophagy.
2026 ・ Pain ・ PMID 41143867
hydrogen-rich water
positive
animal study
Hydrogen-rich water attenuates radiation-induced oral mucositis in mice via antioxidant and gut microbiota-stabilizing effects: a longitudinal study.
2025 ・ Gut Microbes Rep ・ PMID 41909889
hydrogen-rich water
positive
animal study
Gut microbiota as a central mediator in hydrogen gas-induced alleviation of colitis via TLR4/NF-κB and Nrf2 pathway regulation.
2025 ・ Int Immunopharmacol ・ PMID 41076929
inhalation
positive
animal study
Hydrogen-rich gas enhances mitochondrial membrane potential and respiratory function recovery in Caco-2 cells post-ischemia-reperfusion injury.
2025 ・ Biochem Biophys Res Commun ・ PMID 41043278
in vitro
positive
in vitro study
Clinical Efficacy of Hydrogen Therapy on Acute Radiation Enteritis and Inflammatory Response in Patients with Cervical Cancer Undergoing Concurrent Chemoradiation Therapy.
2025 ・ Adv Radiat Oncol ・ PMID 41020280
inhalation
positive
human randomized controlled trial
Advances in Hydrodechlorination Technologies for Diclofenac Removal from Aqueous Systems.
2025 ・ Molecules ・ PMID 40871486
not specified
not assessed
review
Molecular hydrogen therapy: A "democratic" emerging strategy against aging and age-related diseases.
2025 ・ Ageing Res Rev ・ PMID 40518021
mixed routes
not assessed
review
Molecular Hydrogen Therapy: Mechanisms, Delivery Methods, Preventive, and Therapeutic Application.
2025 ・ MedComm (2020) ・ PMID 40297245
mixed routes
not assessed
review
Hydrogen and Methane Detection in Breath in Response to Two Different Types of Dietary Fiber and Its Relationship to Postprandial Glucose Concentration in Obese Patients with Type 2 Diabetes and Normoglycemic Subjects.
2025 ・ Nutrients ・ PMID 40077785
not specified
mixed
human observational study
Thermally processed rice starch impacts glucose homeostasis in mice to different degrees via disturbing gut microbial structure and intestinal barrier function.
2025 ・ Carbohydr Polym ・ PMID 39562071
not specified
not assessed
animal study
Hydrogen-rich water alleviates asthma airway inflammation by modulating tryptophan metabolism and activating aryl hydrocarbon receptor via gut microbiota regulation.
2024 ・ Free Radic Biol Med ・ PMID 39147072
hydrogen-rich water
positive
animal study
An ethically guided preclinical device for phenotyping H2 production in laboratory rodents.
2024 ・ Animal Model Exp Med ・ PMID 38925626
not specified
not assessed
animal study
Light-Operated Transient Unilateral Adhesive Hydrogel for Comprehensive Prevention of Postoperative Adhesions.
2024 ・ Adv Sci (Weinh) ・ PMID 38924679
in vitro
positive
animal study
Hydrogen-rich water alleviates constipation by attenuating oxidative stress through the sirtuin1/nuclear factor-erythroid-2-related factor 2/heme oxygenase-1 signaling pathway.
2024 ・ World J Gastroenterol ・ PMID 38855154
hydrogen-rich water
positive
animal study
Health Benefits of Electrolyzed Hydrogen Water: Antioxidant and Anti-Inflammatory Effects in Living Organisms.
2024 ・ Antioxidants (Basel) ・ PMID 38539846
hydrogen-rich water
not assessed
review
A preliminary therapeutic study of the effects of molecular hydrogen on intestinal dysbiosis and small intestinal injury in high-fat diet-loaded senescence-accelerated mice.
2024 ・ Nutrition ・ PMID 38428218
hydrogen-rich water
positive
animal study
Attenuation of pulmonary damage in aged lipopolysaccharide-induced inflammation mice through continuous 2 % hydrogen gas inhalation: A potential therapeutic strategy for geriatric inflammation and survival.
2023 ・ Exp Gerontol ・ PMID 37572992
inhalation
mixed
animal study
APOA2: New Target for Molecular Hydrogen Therapy in Sepsis-Related Lung Injury Based on Proteomic and Genomic Analysis.
2023 ・ Int J Mol Sci ・ PMID 37511084
animal model
positive
animal study
Effects of Coenzyme Q10 on the Biomarkers (Hydrogen, Methane, SCFA and TMA) and Composition of the Gut Microbiome in Rats.
2023 ・ Pharmaceuticals (Basel) ・ PMID 37242469
animal model
positive
animal study
Novel therapeutic approaches based on the pathological role of gut dysbiosis on the link between nonalcoholic fatty liver disease and insulin resistance.
2023 ・ Eur Rev Med Pharmacol Sci ・ PMID 36930488
hydrogen-rich water
not assessed
review
The overlooked benefits of hydrogen-producing bacteria.
2023 ・ Med Gas Res ・ PMID 36571374
not specified
not assessed
review
Ameliorating Role of Hydrogen-Rich Water Against NSAID-Induced Enteropathy via Reduction of ROS and Production of Short-Chain Fatty Acids.
2023 ・ Dig Dis Sci ・ PMID 36478314
hydrogen-rich water
positive
animal study
1 / 3
Next →