H₂
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lipid peroxidation
238 papers
Delivery-method distribution
hydrogen-rich water: 122
injection / infusion: 27
in vitro: 26
inhalation: 23
mixed routes: 21
not specified: 7
topical application: 5
animal model: 4
hydrogen bath: 3
Molecular hydrogen regulates gene expression by modifying the free radical chain reaction-dependent generation of oxidized phospholipid mediators.
2016 ・ Sci Rep ・ PMID 26739257
in vitro
positive
in vitro study
Postconditioning with inhaled hydrogen promotes survival of retinal ganglion cells in a rat model of retinal ischemia/reperfusion injury.
2016 ・ Brain Res ・ PMID 26705611
inhalation
positive
animal study
Hydrogen-rich water-alleviated ultraviolet-B-triggered oxidative damage is partially associated with the manipulation of the metabolism of (iso)flavonoids and antioxidant defence in Medicago sativa.
2015 ・ Funct Plant Biol ・ PMID 32480752
hydrogen-rich water
positive
other
[Effects of hydrogen rich water on the expression of Nrf 2 and the oxidative stress in rats with traumatic brain injury].
2015 ・ Zhonghua Wei Zhong Bing Ji Jiu Yi Xue ・ PMID 27132459
injection / infusion
positive
animal study
Sirtuin Type 1 Mediates the Retinal Protective Effect of Hydrogen-Rich Saline Against Light-Induced Damage in Rats.
2015 ・ Invest Ophthalmol Vis Sci ・ PMID 26720481
injection / infusion
positive
animal study
Cadmium-Induced Hydrogen Accumulation Is Involved in Cadmium Tolerance in Brassica campestris by Reestablishment of Reduced Glutathione Homeostasis.
2015 ・ PLoS One ・ PMID 26445361
hydrogen-rich water
positive
in vitro study
Molecular hydrogen stabilizes atherosclerotic plaque in low-density lipoprotein receptor-knockout mice.
2015 ・ Free Radic Biol Med ・ PMID 26117323
mixed routes
positive
animal study
Hydrogen ameliorates pulmonary hypertension in rats by anti-inflammatory and antioxidant effects.
2015 ・ J Thorac Cardiovasc Surg ・ PMID 26095621
hydrogen-rich water
positive
animal study
Maternal molecular hydrogen treatment attenuates lipopolysaccharide-induced rat fetal lung injury.
2015 ・ Free Radic Res ・ PMID 25947958
mixed routes
positive
animal study
Hydrogen improves neurological function through attenuation of blood-brain barrier disruption in spontaneously hypertensive stroke-prone rats.
2015 ・ BMC Neurosci ・ PMID 25925889
hydrogen-rich water
positive
animal study
Hydrogen-rich water protects against acetaminophen-induced hepatotoxicity in mice.
2015 ・ World J Gastroenterol ・ PMID 25892869
hydrogen-rich water
positive
animal study
Hydrogen-rich water enhances cadmium tolerance in Chinese cabbage by reducing cadmium uptake and increasing antioxidant capacities.
2015 ・ J Plant Physiol ・ PMID 25543863
in vitro
positive
other
[Protective effects of inhaled hydrogen gas on cognitive function in mice with sepsis-associated encephalopathy].
2014 ・ Zhonghua Yi Xue Za Zhi ・ PMID 25573317
inhalation
positive
animal study
Inhaled hydrogen gas therapy for prevention of noise-induced hearing loss through reducing reactive oxygen species.
2014 ・ Neurosci Res ・ PMID 25196919
inhalation
positive
animal study
Hydrogen protects auditory hair cells from cisplatin-induced free radicals.
2014 ・ Neurosci Lett ・ PMID 25064701
in vitro
positive
in vitro study
Oral intake of hydrogen-rich water ameliorated chlorpyrifos-induced neurotoxicity in rats.
2014 ・ Toxicol Appl Pharmacol ・ PMID 24967689
hydrogen-rich water
positive
animal study
Molecular hydrogen attenuates neuropathic pain in mice.
2014 ・ PLoS One ・ PMID 24941001
hydrogen-rich water
positive
animal study
Therapeutic efficacy of infused molecular hydrogen in saline on rheumatoid arthritis: a randomized, double-blind, placebo-controlled pilot study.
2014 ・ Int Immunopharmacol ・ PMID 24929023
injection / infusion
positive
human randomized controlled trial
Hydrogen-rich saline promotes survival of retinal ganglion cells in a rat model of optic nerve crush.
2014 ・ PLoS One ・ PMID 24915536
injection / infusion
positive
animal study
Hydrogen-rich water confers plant tolerance to mercury toxicity in alfalfa seedlings.
2014 ・ Ecotoxicol Environ Saf ・ PMID 24793520
hydrogen-rich water
positive
in vitro study
Effect of hydrogen-rich water on acute peritonitis of rat models.
2014 ・ Int Immunopharmacol ・ PMID 24793096
hydrogen-rich water
positive
animal study
Hydrogen-rich water delays postharvest ripening and senescence of kiwifruit.
2014 ・ Food Chem ・ PMID 24629944
hydrogen-rich water
positive
other
Dose-dependent inhibition of gastric injury by hydrogen in alkaline electrolyzed drinking water.
2014 ・ BMC Complement Altern Med ・ PMID 24589018
hydrogen-rich water
positive
animal study
Protective role of hydrogen-rich water on aspirin-induced gastric mucosal damage in rats.
2014 ・ World J Gastroenterol ・ PMID 24587639
hydrogen-rich water
positive
animal study
Maternal molecular hydrogen administration ameliorates rat fetal hippocampal damage caused by in utero ischemia-reperfusion.
2014 ・ Free Radic Biol Med ・ PMID 24509162
hydrogen-rich water
positive
animal study
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