H₂
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lipid peroxidation
238 papers
Delivery-method distribution
hydrogen-rich water: 122
injection / infusion: 27
in vitro: 26
inhalation: 23
mixed routes: 21
not specified: 7
topical application: 5
animal model: 4
hydrogen bath: 3
Effect of a hydrogen (H2)-enriched solution on the albumin redox of hemodialysis patients.
2014 ・ Hemodial Int ・ PMID 24274030
injection / infusion
positive
human randomized controlled trial
Effect of Treadmill Exercise and Hydrogen-rich Water Intake on Serum Oxidative and Anti-oxidative Metabolites in Serum of Thoroughbred Horses.
2013 ・ J Equine Sci ・ PMID 24833996
hydrogen-rich water
positive
animal study
Alleviation of cadmium toxicity in Medicago sativa by hydrogen-rich water.
2013 ・ J Hazard Mater ・ PMID 23846121
hydrogen-rich water
positive
in vitro study
Molecular hydrogen attenuates fatty acid uptake and lipid accumulation through downregulating CD36 expression in HepG2 cells.
2013 ・ Med Gas Res ・ PMID 23448206
in vitro
positive
in vitro study
Lactulose mediates suppression of dextran sodium sulfate-induced colon inflammation by increasing hydrogen production.
2013 ・ Dig Dis Sci ・ PMID 23371012
mixed routes
positive
animal study
Treatment of hydrogen molecule abates oxidative stress and alleviates bone loss induced by modeled microgravity in rats.
2013 ・ Osteoporos Int ・ PMID 22648000
mixed routes
positive
animal study
H(2) gas improves functional outcome after cardiac arrest to an extent comparable to therapeutic hypothermia in a rat model.
2012 ・ J Am Heart Assoc ・ PMID 23316300
inhalation
positive
animal study
Consumption of water containing a high concentration of molecular hydrogen reduces oxidative stress and disease activity in patients with rheumatoid arthritis: an open-label pilot study.
2012 ・ Med Gas Res ・ PMID 23031079
hydrogen-rich water
positive
human observational study
Protective effects of hydrogen-rich saline in a rat model of permanent focal cerebral ischemia via reducing oxidative stress and inflammatory cytokines.
2012 ・ Brain Res ・ PMID 23010312
injection / infusion
positive
animal study
Therapeutic effects of hydrogen saturated saline on rat diabetic model and insulin resistant model via reduction of oxidative stress.
2012 ・ Chin Med J (Engl) ・ PMID 22800834
injection / infusion
positive
animal study
Hydrogen-rich water inhibits glucose and α,β -dicarbonyl compound-induced reactive oxygen species production in the SHR.Cg-Leprcp/NDmcr rat kidney.
2012 ・ Med Gas Res ・ PMID 22776773
hydrogen-rich water
positive
animal study
Hydrogen-rich water prevents lipid deposition in the descending aorta in a rat periodontitis model.
2012 ・ Arch Oral Biol ・ PMID 22607937
hydrogen-rich water
positive
animal study
Beneficial effect of hydrogen-rich saline on cerebral vasospasm after experimental subarachnoid hemorrhage in rats.
2012 ・ J Neurosci Res ・ PMID 22589232
injection / infusion
positive
animal study
Pilot study: Effects of drinking hydrogen-rich water on muscle fatigue caused by acute exercise in elite athletes.
2012 ・ Med Gas Res ・ PMID 22520831
hydrogen-rich water
positive
human randomized controlled trial
Hydrogen-rich water prevents progression of nonalcoholic steatohepatitis and accompanying hepatocarcinogenesis in mice.
2012 ・ Hepatology ・ PMID 22505328
hydrogen-rich water
positive
animal study
Hydrogen gas ameliorates oxidative stress in early brain injury after subarachnoid hemorrhage in rats.
2012 ・ Crit Care Med ・ PMID 22336722
inhalation
positive
animal study
Oral intake of hydrogen-rich water inhibits intimal hyperplasia in arterialized vein grafts in rats.
2012 ・ Cardiovasc Res ・ PMID 22287575
hydrogen-rich water
positive
animal study
Hydrogen-rich saline prevents neointima formation after carotid balloon injury by suppressing ROS and the TNF-α/NF-κB pathway.
2012 ・ Atherosclerosis ・ PMID 22153150
injection / infusion
positive
animal study
Open-label trial and randomized, double-blind, placebo-controlled, crossover trial of hydrogen-enriched water for mitochondrial and inflammatory myopathies.
2011 ・ Med Gas Res ・ PMID 22146674
hydrogen-rich water
mixed
human randomized controlled trial
Molecular hydrogen protects chondrocytes from oxidative stress and indirectly alters gene expressions through reducing peroxynitrite derived from nitric oxide.
2011 ・ Med Gas Res ・ PMID 22146365
in vitro
positive
in vitro study
Hydrogen-rich water attenuates experimental periodontitis in a rat model.
2011 ・ J Clin Periodontol ・ PMID 22092571
hydrogen-rich water
positive
animal study
Effect of molecular hydrogen saturated alkaline electrolyzed water on disuse muscle atrophy in gastrocnemius muscle.
2011 ・ J Physiol Anthropol ・ PMID 21963827
hydrogen-rich water
mixed
animal study
Protective effect of hydrogen-rich saline on decompression sickness in rats.
2011 ・ Aviat Space Environ Med ・ PMID 21702310
injection / infusion
positive
animal study
Consumption of hydrogen water reduces paraquat-induced acute lung injury in rats.
2011 ・ J Biomed Biotechnol ・ PMID 21318114
hydrogen-rich water
positive
animal study
Molecular hydrogen improves obesity and diabetes by inducing hepatic FGF21 and stimulating energy metabolism in db/db mice.
2011 ・ Obesity (Silver Spring) ・ PMID 21293445
hydrogen-rich water
positive
animal study
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