H₂
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lipid peroxidation
238 papers
Delivery-method distribution
hydrogen-rich water: 122
injection / infusion: 27
in vitro: 26
inhalation: 23
mixed routes: 21
not specified: 7
topical application: 5
animal model: 4
hydrogen bath: 3
A randomized, placebo-controlled clinical trial of hydrogen/oxygen inhalation for non-alcoholic fatty liver disease.
2022 ・ J Cell Mol Med ・ PMID 35734974
mixed routes
positive
human randomized controlled trial
Long-term and daily use of molecular hydrogen induces reprogramming of liver metabolism in rats by modulating NADP/NADPH redox pathways.
2022 ・ Sci Rep ・ PMID 35273249
mixed routes
positive
animal study
Effects of hydrogen-rich water and ascorbic acid treatment on spontaneously hypertensive rats.
2022 ・ Exp Anim ・ PMID 35264492
hydrogen-rich water
positive
animal study
Hydrogen-rich water exerts anti-tumor effects comparable to 5-fluorouracil in a colorectal cancer xenograft model.
2022 ・ World J Gastrointest Oncol ・ PMID 35116114
hydrogen-rich water
positive
animal study
Evaluation of the hydrogen-rich water alleviation potential on mercury toxicity in earthworms using ATR-FTIR and LC-ESI-MS/MS spectroscopy.
2022 ・ Environ Sci Pollut Res Int ・ PMID 34718956
injection / infusion
positive
animal study
Attenuation of Myocardial Fibrosis Using Molecular Hydrogen by Inhibiting the TGF-β Signaling Pathway in Spontaneous Hypertensive Rats.
2022 ・ Am J Hypertens ・ PMID 34618887
injection / infusion
positive
animal study
Hydrogen-Rich Water Alleviates the Nickel-Induced Toxic Responses (Inflammatory Responses, Oxidative Stress, DNA Damage) and Ameliorates Cocoon Production in Earthworm.
2022 ・ Biol Trace Elem Res ・ PMID 34482505
hydrogen-rich water
positive
animal study
Hydrogen-rich water reduced oxidative stress and renal fibrosis in rats with unilateral ureteral obstruction.
2022 ・ Pediatr Res ・ PMID 34365467
hydrogen-rich water
positive
animal study
Hydrogen Rich Water Consumption Positively Affects Muscle Performance, Lactate Response, and Alleviates Delayed Onset of Muscle Soreness After Resistance Training.
2022 ・ J Strength Cond Res ・ PMID 33555824
hydrogen-rich water
positive
human randomized controlled trial
The Role of Hyperthermia in Methamphetamine-Induced Depression-Like Behaviors: Protective Effects of Coral Calcium Hydride.
2021 ・ Front Mol Neurosci ・ PMID 35058751
animal model
positive
animal study
The Therapeutic Effects of Oral Intake of Hydrogen Rich Water on Cutaneous Wound Healing in Dogs.
2021 ・ Vet Sci ・ PMID 34822637
hydrogen-rich water
positive
animal study
Protective Effect of Molecular Hydrogen Following Different Routes of Administration on D-Galactose-Induced Aging Mice.
2021 ・ J Inflamm Res ・ PMID 34737603
mixed routes
positive
animal study
Effect of hydrogen-rich water on the lactic acid level in metformin-treated diabetic rats under hypoxia.
2021 ・ Korean J Physiol Pharmacol ・ PMID 34697262
hydrogen-rich water
positive
animal study
Inhalation of 2% Hydrogen Improves Survival Rate and Attenuates Shedding of Vascular Endothelial Glycocalyx in Rats with Heat Stroke.
2021 ・ Shock ・ PMID 34524269
inhalation
positive
animal study
Application of Molecular Hydrogen in Heart Surgery under Cardiopulmonary Bypass.
2021 ・ Sovrem Tekhnologii Med ・ PMID 34513069
inhalation
positive
human observational study
Prenatal Molecular Hydrogen Administration Ameliorates Several Findings in Nitrofen-Induced Congenital Diaphragmatic Hernia.
2021 ・ Int J Mol Sci ・ PMID 34502408
hydrogen-rich water
positive
animal study
Oral Hydrogen-Rich Water Alleviates Oxalate-Induced Kidney Injury by Suppressing Oxidative Stress, Inflammation, and Fibrosis.
2021 ・ Front Med (Lausanne) ・ PMID 34490303
hydrogen-rich water
positive
animal study
Molecular Hydrogen Maintains the Storage Quality of Chinese Chive through Improving Antioxidant Capacity.
2021 ・ Plants (Basel) ・ PMID 34072565
inhalation
positive
other
Hydrogen alleviates acute lung injury induced by limb ischaemia/reperfusion in mice.
2021 ・ Life Sci ・ PMID 34052293
injection / infusion
positive
animal study
Combined treatment with dissolved hydrogen molecule and platinum nanocolloid exerts carcinostatic/carcinocidal effects by increasing hydrogen peroxide generation and cell death in the human gastric cancer cell line NUGC-4.
2021 ・ Free Radic Res ・ PMID 33929281
in vitro
positive
in vitro study
Effects of hydrogen as adjuvant treatment for unstable angina.
2021 ・ Exp Biol Med (Maywood) ・ PMID 33899541
mixed routes
positive
human randomized controlled trial
The protective effect of hydrogen-rich water on rats with type 2 diabetes mellitus.
2021 ・ Mol Cell Biochem ・ PMID 33830396
hydrogen-rich water
positive
animal study
[THE USE OF MOLECULAR HYDROGEN IN CORRECTION OF NO-REFLOW SYNDROME IN THE POLYURIC STAGE OF SUBLIMATE NEPHROPATHY].
2021 ・ Georgian Med News ・ PMID 33814411
hydrogen-rich water
positive
animal study
Hydrogen Nano-Bubble Water Suppresses ROS Generation, Adipogenesis, and Interleukin-6 Secretion in Hydrogen-Peroxide- or PMA-Stimulated Adipocytes and Three-Dimensional Subcutaneous Adipose Equivalents.
2021 ・ Cells ・ PMID 33799840
in vitro
positive
in vitro study
Protective effects of hydrogen rich saline solution on ventral penile mathieu type flap with penile tourniquet application in rats.
2021 ・ J Pediatr Urol ・ PMID 33608226
injection / infusion
positive
animal study
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