H₂
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oxidative stress
899 papers
Delivery-method distribution
hydrogen-rich water: 313
inhalation: 153
mixed routes: 150
in vitro: 103
injection / infusion: 72
not specified: 66
topical application: 19
animal model: 15
hydrogen bath: 8
Mechanism of hydrogen-rich water alleviating radiation-induced cognitive impairment through PI3K/AKT/Caspase-9 pathway mediating anti-oxidation.
2025 ・ Mol Cell Biochem ・ PMID 40646375
hydrogen-rich water
positive
animal study
Delivery of Molecular Hydrogen for Precision Immunomodulation: Mechanisms, Detection Methods, and Applications.
2025 ・ Adv Sci (Weinh) ・ PMID 40619605
mixed routes
not assessed
review
Predicting Therapeutic Response to Molecular Hydrogen in Autoimmune Diseases via Immunophenotyping.
2025 ・ APMIS ・ PMID 40590161
hydrogen-rich water
mixed
human observational study
Molecular Hydrogen Therapy in Rheumatoid Arthritis: A Case Report on the Amelioration of Methotrexate-induced Myelosuppression and Immune Modulation.
2025 ・ In Vivo ・ PMID 40579028
not specified
positive
human case report
Molecular Hydrogen as an Adjuvant Therapy in Comorbid Sjögren's Syndrome, SLE, and ILD: A Case Report on Immune Modulation and Fatigue Reduction.
2025 ・ In Vivo ・ PMID 40579023
mixed routes
positive
human case report
Hydrogen-powered bacteria enhance organic micropollutant degradation under starvation conditions.
2025 ・ Water Res ・ PMID 40578101
in vitro
positive
other
Molecular hydrogen as a novel regulator of cellular pyroptosis: mechanistic insights and therapeutic implications.
2025 ・ Mol Biol Rep ・ PMID 40569354
not specified
not assessed
review
Topically Applied Molecular Hydrogen Normalizes Skin Parameters Associated with Oxidative Stress: A Pilot Study.
2025 ・ Antioxidants (Basel) ・ PMID 40563361
topical application
positive
human case report
The effects of drinking hydrogen-rich water for six weeks on exercise-related biomarkers in exercise-naïve men and women over 50 years following resistance training program: a randomized controlled pilot trial.
2025 ・ Res Sports Med ・ PMID 40525414
hydrogen-rich water
positive
human randomized controlled trial
Molecular hydrogen therapy: A "democratic" emerging strategy against aging and age-related diseases.
2025 ・ Ageing Res Rev ・ PMID 40518021
mixed routes
not assessed
review
Comparison of the Antimicrobial Effect of Hydrogen Water and Chlorhexidine Mouth rinse in Toothbrush Disinfection Among Dental Students.
2025 ・ J Pharm Bioallied Sci ・ PMID 40511014
hydrogen-rich water
positive
human randomized controlled trial
Coaxial Fibrous Dressing Enabling Sequential NO/HRelease for Temporally Programmed Antibacterial and Healing-Promoting Functions in Infected Diabetic Wound Treatment.
2025 ・ ACS Appl Mater Interfaces ・ PMID 40504663
topical application
positive
animal study
Role of Cholesterol in Mediating Interaction of Antidepressant Amitriptyline with Phospholipid Membranes.
2025 ・ Langmuir ・ PMID 40492616
in vitro
not assessed
in vitro study
Local Visible-Photocatalytic Production of Hydrogen and Warm Heat for Combination Treatment of Pressure Ulcer.
2025 ・ Adv Sci (Weinh) ・ PMID 40491331
topical application
positive
animal study
Molecular hydrogen mitigates NEMP-induced male reproductive cells apoptosis via scavenging ROS.
2025 ・ Electromagn Biol Med ・ PMID 40476593
in vitro
positive
in vitro study
Fresh apple slice preservation driven by molecular hydrogen.
2025 ・ Food Chem ・ PMID 40446655
in vitro
positive
other
Redox reactions in chronic pain: mechanisms and relevance in fibromyalgia.
2025 ・ Front Pain Res (Lausanne) ・ PMID 40432823
not specified
not assessed
review
Hydrogen activates ACOD1-itaconate pathway to ameliorate steroid-associated osteonecrosis.
2025 ・ Biomaterials ・ PMID 40411985
hydrogen-rich water
positive
animal study
Treatment with hydrogen-rich water protects against thioacetamide-induced hepatic encephalopathy in rats through stabilizing liver-brain disturbance.
2025 ・ Sci Rep ・ PMID 40410340
hydrogen-rich water
positive
animal study
Molecular hydrogen mitigates traumatic brain injury-induced lung injury via NLRP3 inflammasome inhibition.
2025 ・ BMC Chem ・ PMID 40405232
inhalation
positive
animal study
Hydrogen-Rich Water Decreases Muscle Damage and Improves Power Endurance in Elite Athletes: A Randomized, Double-Blinded, Placebo-Controlled Trial.
2025 ・ J Lifestyle Med ・ PMID 40376695
hydrogen-rich water
positive
human randomized controlled trial
Molecular Hydrogen Ameliorates Anti-Desmoglein 1 Antibody-Induced Pemphigus-Associated Interstitial Lung Disease by Inhibiting Oxidative Stress.
2025 ・ Int J Mol Sci ・ PMID 40362440
hydrogen-rich water
positive
animal study
Molecular Hydrogen in the Treatment of Respiratory Diseases.
2025 ・ Int J Mol Sci ・ PMID 40362357
mixed routes
not assessed
review
Role and mechanism of molecular hydrogen in the treatment of Parkinson's diseases.
2025 ・ Front Neurosci ・ PMID 40336538
mixed routes
mixed
review
[Efficiency and safety of the integrated use of medical gases thermal heliox, nitric oxide and molecular hydrogen in patients with exacerbation of chronic obstructive pulmonary disease complicated by hypoxemic, hypercapnic respiratory failure and secondary pulmonary arterial hypertension in the post-COVID period].
2025 ・ Ter Arkh ・ PMID 40327618
inhalation
positive
human randomized controlled trial
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