H₂
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oxidative stress
899 papers
Delivery-method distribution
hydrogen-rich water: 313
inhalation: 153
mixed routes: 150
in vitro: 103
injection / infusion: 72
not specified: 66
topical application: 19
animal model: 15
hydrogen bath: 8
Dissolved molecular hydrogen (H) in Peritoneal Dialysis (PD) solutions preserves mesothelial cells and peritoneal membrane integrity.
2017 ・ BMC Nephrol ・ PMID 29089029
injection / infusion
positive
animal study
Efficacy of inhaled HYdrogen on neurological outcome following BRain Ischemia During post-cardiac arrest care (HYBRID II trial): study protocol for a randomized controlled trial.
2017 ・ Trials ・ PMID 29058596
inhalation
not assessed
human randomized controlled trial
Hydrogen gas attenuates sevoflurane neurotoxicity through inhibiting nuclear factor κ-light-chain-enhancer of activated B cells signaling and proinflammatory cytokine release in neonatal rats.
2017 ・ Neuroreport ・ PMID 28926473
inhalation
positive
animal study
Possible clinical effects of molecular hydrogen (H2) delivery during hemodialysis in chronic dialysis patients: Interim analysis in a 12 month observation.
2017 ・ PLoS One ・ PMID 28902900
injection / infusion
positive
human observational study
Molecular hydrogen modulates gene expression via histone modification and induces the mitochondrial unfolded protein response.
2017 ・ Biochem Biophys Res Commun ・ PMID 28890349
animal model
positive
animal study
Molecular hydrogen increases resilience to stress in mice.
2017 ・ Sci Rep ・ PMID 28852144
inhalation
positive
animal study
Hydrogen-rich pure water prevents cigarette smoke-induced pulmonary emphysema in SMP30 knockout mice.
2017 ・ Biochem Biophys Res Commun ・ PMID 28807355
hydrogen-rich water
positive
animal study
Anti-oxidant and anti-inflammatory effects of hydrogen-rich water alleviate ethanol-induced fatty liver in mice.
2017 ・ World J Gastroenterol ・ PMID 28785146
hydrogen-rich water
positive
animal study
Molecular hydrogen in the treatment of acute and chronic neurological conditions: mechanisms of protection and routes of administration.
2017 ・ J Clin Biochem Nutr ・ PMID 28751802
mixed routes
not assessed
review
Protective effects of hydrogen rich water on the intestinal ischemia/reperfusion injury due to intestinal intussusception in a rat model.
2017 ・ Med Gas Res ・ PMID 28744362
injection / infusion
positive
animal study
Influence of hydrogen-occluding-silica on migration and apoptosis in human esophageal cells.
2017 ・ Med Gas Res ・ PMID 28744359
in vitro
mixed
in vitro study
Hydrogen-rich medium protects mouse embryonic fibroblasts from oxidative stress by activating LKB1-AMPK-FoxO1 signal pathway.
2017 ・ Biochem Biophys Res Commun ・ PMID 28743498
in vitro
positive
in vitro study
Hydrogen Gas Inhalation Treatment in Acute Cerebral Infarction: A Randomized Controlled Clinical Study on Safety and Neuroprotection.
2017 ・ J Stroke Cerebrovasc Dis ・ PMID 28669654
inhalation
positive
human randomized controlled trial
Impact of molecular hydrogen treatments on the innate immune activity and survival of zebrafish (Danio rerio) challenged with Aeromonas hydrophila.
2017 ・ Fish Shellfish Immunol ・ PMID 28630014
hydrogen-rich water
positive
animal study
[Effect of hydrogen-rich water on the CD34 expression in lesion boundary brain tissue of rats with traumatic brain injury].
2017 ・ Zhonghua Wei Zhong Bing Ji Jiu Yi Xue ・ PMID 28627348
injection / infusion
positive
animal study
Hydrogen gas protects IP3Rs by reducing disulfide bridges in human keratinocytes under oxidative stress.
2017 ・ Sci Rep ・ PMID 28620198
in vitro
positive
in vitro study
Molecular hydrogen inhalation attenuates postoperative cognitive impairment in rats.
2017 ・ Neuroreport ・ PMID 28614179
inhalation
positive
animal study
Hydrogen generation by reaction of Si nanopowder with neutral water.
2017 ・ J Nanopart Res ・ PMID 28579914
in vitro
not assessed
other
Hydrogen-rich water alleviates the toxicities of different stresses to mycelial growth in Hypsizygus marmoreus.
2017 ・ AMB Express ・ PMID 28565883
in vitro
positive
in vitro study
Molecular hydrogen protects against oxidative stress-induced SH-SY5Y neuroblastoma cell death through the process of mitohormesis.
2017 ・ PLoS One ・ PMID 28467497
in vitro
positive
in vitro study
Complexity of Stomach-Brain Interaction Induced by Molecular Hydrogen in Parkinson's Disease Model Mice.
2017 ・ Neurochem Res ・ PMID 28462451
hydrogen-rich water
positive
animal study
Hydrogen Rich Water Attenuates Renal Injury and Fibrosis by Regulation Transforming Growth Factor-β Induced Sirt1.
2017 ・ Biol Pharm Bull ・ PMID 28458345
hydrogen-rich water
positive
animal study
Does HAlter Mitochondrial Bioenergetics via GHS-R1α Activation?
2017 ・ Theranostics ・ PMID 28435468
not specified
not assessed
other
Molecular Hydrogen Effectively Heals Alkali-Injured Cornea via Suppression of Oxidative Stress.
2017 ・ Oxid Med Cell Longev ・ PMID 28400915
topical application
positive
animal study
Therapeutic effects of hydrogen on chronic graft-versus-host disease.
2017 ・ J Cell Mol Med ・ PMID 28374556
injection / infusion
positive
animal study
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