水素ナノバブルと酸化的ウィンドウ：水素濃度の違いが種子発芽およびストレス防御に与える影響の検討
Under cadmium ion (Cd) stress, the maximum germination rate of radish seeds declined from 90% to 50%. Hydrogen nanobubble (NB) water substantially mitigated this inhibitory effect in a concentration-dependent manner. A hydrogen concentration of 0.8 ppm proved optimal, reducing Cd accumulation in seeds by 63.23% and restoring the maximum germination rate from 50% to 65%. At concentrations above 1.2 ppm, the protective effect diminished or reversed. To explain this biphasic response, the authors incorporated the oxidative window concept into a redox balance model, demonstrating that an appropriate hydrogen level maintains intracellular redox homeostasis. Transcriptome sequencing indicated that hydrogen NB water regulated Cd uptake and accumulation by modifying cell wall components, attenuated oxidative stress via oxidoreductase activity, and promoted nutrient synthesis and metabolism, collectively relieving Cd-induced germination inhibition. These findings provide a mechanistic framework for optimizing hydrogen concentration in agricultural applications.
Hydrogen nanobubble water suppresses cadmium uptake by modifying cell wall components and enhancing oxidoreductase activity, maintaining intracellular redox homeostasis within an optimal oxidative window to reduce oxidative stress.
Hydrogen-rich water is a low-risk delivery route, but the achievable systemic hydrogen dose is bounded. For clinical applications, inhalation is the most efficient route; inhalation, however, carries explosion risk, and concentration matters (empirical LFL of 10% applies to inhalation environments; high-concentration devices are documented in the Consumer Affairs Agency accident database and are not recommended).
See also:
https://h2-papers.org/en/papers/38941838