H₂
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topical application
19 papers
Delivery-method distribution
topical application: 16
mixed routes: 2
in vitro: 1
Efficacy of different nasal irrigation treatments versus placebo in allergic rhinitis: a systematic review and network meta-analysis.
2025 ・ Front Pharmacol ・ PMID 41293244
topical application
mixed
meta-analysis
Transdermal hydrogen therapy for psoriasis using cavity-embedded double-conical microneedles.
2025 ・ J Control Release ・ PMID 41083007
topical application
positive
animal study
Local Delivery of Molecular Hydrogen by Fluorinated Zeolitic Imidazole Framework Nanosheets Boosts Cancer Immunotherapy.
2025 ・ ACS Appl Mater Interfaces ・ PMID 40864154
in vitro
positive
in vitro study
Topically Applied Molecular Hydrogen Normalizes Skin Parameters Associated with Oxidative Stress: A Pilot Study.
2025 ・ Antioxidants (Basel) ・ PMID 40563361
topical application
positive
human case report
Coaxial Fibrous Dressing Enabling Sequential NO/HRelease for Temporally Programmed Antibacterial and Healing-Promoting Functions in Infected Diabetic Wound Treatment.
2025 ・ ACS Appl Mater Interfaces ・ PMID 40504663
topical application
positive
animal study
Local Visible-Photocatalytic Production of Hydrogen and Warm Heat for Combination Treatment of Pressure Ulcer.
2025 ・ Adv Sci (Weinh) ・ PMID 40491331
topical application
positive
animal study
Mast Cells in Regeneration of the Skin in Burn Wound with Special Emphasis on Molecular Hydrogen Effect.
2023 ・ Pharmaceuticals (Basel) ・ PMID 36986447
mixed routes
positive
animal study
Two-Dimensional MgSi Nanosheet-Enabled Sustained Hydrogen Generation for Improved Repair and Regeneration of Deeply Burned Skin.
2023 ・ Adv Healthc Mater ・ PMID 36546774
topical application
positive
in vitro study
Hydrogen-producing Photocatalyst at Sunscreen for Athletes in Preventing and Healing Muscle-nerve-skin Injuries.
2023 ・ Curr Top Med Chem ・ PMID 36529921
topical application
not assessed
review
Photocatalytic glucose depletion and hydrogen generation for diabetic wound healing.
2022 ・ Nat Commun ・ PMID 36167814
topical application
positive
animal study
Prophylactic Instillation of Hydrogen-Rich Water Decreases Corneal Inflammation and Promotes Wound Healing by Activating Antioxidant Activity in a Rat Alkali Burn Model.
2022 ・ Int J Mol Sci ・ PMID 36077171
topical application
positive
animal study
Symbiotic Algae-Bacteria Dressing for Producing Hydrogen to Accelerate Diabetic Wound Healing.
2022 ・ Nano Lett ・ PMID 34928162
topical application
positive
in vitro study
Molecular Hydrogen Attenuated N-methyl-N-Nitrosourea Induced Corneal Endothelial Injury by Upregulating Anti-Apoptotic Pathway.
2021 ・ Invest Ophthalmol Vis Sci ・ PMID 34196654
mixed routes
positive
animal study
Antioxidant Activity of Hydrogen Water Mask Pack Composed of Gel-Type Emulsion and Hydrogen Generation Powder.
2020 ・ Int J Mol Sci ・ PMID 33419292
topical application
positive
human observational study
An Immunohistochemical Study of the Increase in Antioxidant Capacity of Corneal Epithelial Cells by Molecular Hydrogen, Leading to the Suppression of Alkali-Induced Oxidative Stress.
2020 ・ Oxid Med Cell Longev ・ PMID 32655773
topical application
positive
animal study
Case Report: Buccal administration of hydrogen-producing blend after a mild traumatic brain injury in a professional athlete.
2019 ・ F1000Res ・ PMID 32595937
topical application
positive
human case report
Accelerated healing of full thickness dermal wounds by macroporous waterborne polyurethane-chitosan hydrogel scaffolds.
2017 ・ Mater Sci Eng C Mater Biol Appl ・ PMID 28887957
topical application
positive
animal study
Molecular Hydrogen Effectively Heals Alkali-Injured Cornea via Suppression of Oxidative Stress.
2017 ・ Oxid Med Cell Longev ・ PMID 28400915
topical application
positive
animal study
Protection of the retina by rapid diffusion of hydrogen: administration of hydrogen-loaded eye drops in retinal ischemia-reperfusion injury.
2010 ・ Invest Ophthalmol Vis Sci ・ PMID 19834032
topical application
positive
animal study