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hydroxyl radical scavenging
352 papers
Delivery-method distribution
hydrogen-rich water: 93
mixed routes: 71
inhalation: 66
in vitro: 41
injection / infusion: 34
not specified: 31
topical application: 9
animal model: 7
Oxidative Stress and Pathways of Molecular Hydrogen Effects in Medicine.
2021 ・ Curr Pharm Des ・ PMID 32954996
not specified
not assessed
review
Molecular Hydrogen Application in Stroke: Bench to Bedside.
2021 ・ Curr Pharm Des ・ PMID 32940172
mixed routes
not assessed
review
Direct Targets and Subsequent Pathways for Molecular Hydrogen to Exert Multiple Functions: Focusing on Interventions in Radical Reactions.
2021 ・ Curr Pharm Des ・ PMID 32767925
not specified
not assessed
review
Hydrogen and therapeutic gases for neonatal hypoxic-ischemic encephalopathy: potential neuroprotective adjuncts in translational research.
2021 ・ Pediatr Res ・ PMID 32505123
inhalation
not assessed
review
Antioxidant Activity of Hydrogen Water Mask Pack Composed of Gel-Type Emulsion and Hydrogen Generation Powder.
2020 ・ Int J Mol Sci ・ PMID 33419292
topical application
positive
human observational study
Impact of hydrogen-rich gas mixture inhalation through nasal cannula during post-exercise recovery period on subsequent oxidative stress, muscle damage, and exercise performances in men.
2020 ・ Med Gas Res ・ PMID 33380581
inhalation
mixed
human randomized controlled trial
The Efficacy of Melanin Precursor QIAPI 1© Against Age-related Macular Degeneration (AMD): A Case Report.
2020 ・ Cent Nerv Syst Agents Med Chem ・ PMID 33167844
topical application
mixed
human case report
Hydrogen gas inhalation alleviates oxidative stress in patients with post-cardiac arrest syndrome.
2020 ・ J Clin Biochem Nutr ・ PMID 33041520
inhalation
mixed
human case report
Effects of hydrogen-rich water prepared by alternating-current-electrolysis on antioxidant activity, DNA oxidative injuries, and diabetes-related markers.
2020 ・ Med Gas Res ・ PMID 33004708
hydrogen-rich water
positive
human observational study
Protective effects of molecular hydrogen on hepatotoxicity induced by sub-chronic exposure to chlorpyrifos in rats.
2020 ・ Ann Agric Environ Med ・ PMID 32955216
hydrogen-rich water
positive
animal study
Longitudinal multiparametric MRI study of hydrogen-enriched water with minocycline combination therapy in experimental ischemic stroke in rats.
2020 ・ Brain Res ・ PMID 32919984
hydrogen-rich water
positive
animal study
Hydrogenases and the Role of Molecular Hydrogen in Plants.
2020 ・ Plants (Basel) ・ PMID 32887396
not specified
not assessed
review
Molecular hydrogen: A potential radioprotective agent.
2020 ・ Biomed Pharmacother ・ PMID 32763820
mixed routes
not assessed
review
Hydrogen gas inhalation improves delayed brain injury by alleviating early brain injury after experimental subarachnoid hemorrhage.
2020 ・ Sci Rep ・ PMID 32704088
inhalation
positive
animal study
An Immunohistochemical Study of the Increase in Antioxidant Capacity of Corneal Epithelial Cells by Molecular Hydrogen, Leading to the Suppression of Alkali-Induced Oxidative Stress.
2020 ・ Oxid Med Cell Longev ・ PMID 32655773
topical application
positive
animal study
Peripheral endothelial function can be improved by daily consumption of water containing over 7 ppm of dissolved hydrogen: A randomized controlled trial.
2020 ・ PLoS One ・ PMID 32470022
hydrogen-rich water
positive
human randomized controlled trial
Constitutive hydrogen inhalation prevents vascular remodeling via reduction of oxidative stress.
2020 ・ PLoS One ・ PMID 32302306
inhalation
positive
animal study
Oral Administration of Si-Based Agent Attenuates Oxidative Stress and Ischemia-Reperfusion Injury in a Rat Model: A Novel Hydrogen Administration Method.
2020 ・ Front Med (Lausanne) ・ PMID 32266279
hydrogen-rich water
positive
animal study
A "philosophical molecule," hydrogen may overcome senescence and intractable diseases.
2020 ・ Med Gas Res ・ PMID 32189669
inhalation
not assessed
review
Hydrogen-rich water suppresses the reduction in blood total antioxidant capacity induced by 3 consecutive days of severe exercise in physically active males.
2020 ・ Med Gas Res ・ PMID 32189665
hydrogen-rich water
positive
human randomized controlled trial
Application of Molecular Hydrogen as a Novel Antioxidant in Sports Science.
2020 ・ Oxid Med Cell Longev ・ PMID 32015786
mixed routes
not assessed
review
Molecular hydrogen regulates PTEN-AKT-mTOR signaling via ROS to alleviate peritoneal dialysis-related peritoneal fibrosis.
2020 ・ FASEB J ・ PMID 31930571
injection / infusion
positive
animal study
Molecular hydrogen suppresses superoxide generation in the mitochondrial complex I and reduced mitochondrial membrane potential.
2020 ・ Biochem Biophys Res Commun ・ PMID 31810604
in vitro
positive
in vitro study
Protective effects of a hydrogen-rich solution during cold ischemia in rat lung transplantation.
2020 ・ J Thorac Cardiovasc Surg ・ PMID 31780065
injection / infusion
positive
animal study
Effect of Hydrogen-Rich Water on Radiation-Induced Cognitive Dysfunction in Rats.
2020 ・ Radiat Res ・ PMID 31634054
hydrogen-rich water
positive
animal study
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